PRMT1 and SAMD3

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		PRMT1	SAMD3
Gene Name		protein arginine methyltransferase 1	sterile alpha motif domain containing 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Methyltransferase Activity N-methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Identical Protein Binding Histone Methyltransferase Activity (H4-R3 Specific) Poly(A) RNA Binding	Protein Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Protein Methylation Cell Surface Receptor Signaling Pathway Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Neuron Projection Development Histone H4-R3 Methylation Negative Regulation Of Megakaryocyte Differentiation
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		93 interactors: AR ARPC3 ASH2L AXIN1 BRCA1 BTG1 BTG2 C17orf53 C20orf196 C4orf17 CAPRIN1 CDC37 CEP162 CIRBP CNOT8 COIL DAXX DCAF16 DCAF8 DHX9 EIF4A1 ESR1 EWSR1 FAM83D FAM9A FBL FGF2 FLII FUS GPATCH2L GRHL3 GRIP1 HABP4 HIST1H3A HIST1H4A HIST2H4A HIST4H4 HNF4A HNRNPA1 HNRNPK HNRNPR HNRNPU HNRNPUL1 IDH3B IFNAR1 IGSF21 ILF3 KHDRBS1 KHDRBS2 KHDRBS3 LRIF1 MBP MECOM MED31 MLST8 NCOA1 NCOA2 NCOA3 NOL4 NRIP1 OFCC1 PIAS1 PPARA PRMT8 QKI RELA RNF187 RUNX1 S100A8 SAMD3 SPAG8 SPEG SPSB1 SPSB2 STAT1 STAT5A SUPT5H SYNCRIP TAF15 TBX6 TERF2 THRB TP53 VHL VPS72 WDFY3 WDR33 WDYHV1 YLPM1 YWHAG ZBTB14 ZMYM5 ZNF451	7 interactors: AKAP9 C6orf165 FANCG HSPD1 KDM1A LMO3 PRMT1
Entrez ID		3276	154075
HPRD ID		04257	11530
Ensembl ID		ENSG00000126457	ENSG00000164483
Uniprot IDs		B4DJ87 H7C2I1 Q99873	B4DY20 J3KQK4 Q8N6K7
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Gene Expression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Androgen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process MRNA Processing Chromatin Organization Cellular Process Chromatin Modification Response To Hormone MRNA Metabolic Process RNA Processing Chromosome Organization Cellular Response To Hormone Stimulus Metabolic Process Response To Organic Substance	Regulation Of Megakaryocyte Differentiation Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Glucocorticoid Receptor Signaling Pathway B Cell Cytokine Production Isotype Switching To IgG Isotypes Regulation Of Primitive Erythrocyte Differentiation Cell Development Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Regulation Of Myeloid Cell Differentiation System Development Negative Regulation Of Megakaryocyte Differentiation Gonad Development Development Of Primary Sexual Characteristics Multicellular Organismal Development Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Anatomical Structure Development Positive Regulation Of Immune Response To Tumor Cell Sex Differentiation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Immune System Process Positive Regulation Of Hormone Biosynthetic Process Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Macrophage Activation Peptidyl-arginine N-methylation Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Developmental Process Histone H4-R3 Methylation Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Chaperone-mediated Protein Complex Assembly Cytokine Production Involved In Immune Response Organelle Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Histone Modification Granulocyte Differentiation Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Potassium Ion Transmembrane Transport Histone Arginine Methylation Positive Regulation Of Interferon-alpha Production Peptidyl-arginine Methylation Negative Regulation Of Histone Methylation Regulation Of Cell Differentiation
Tagcloud ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	adjacent androgen androgens antagonistic antagonistically ar btg1 cdca7l cdk6 chip confirming depends find htgp immunoprecipitation mapped position prostate proved publicly ra rar rare responsive restricted retinoic seq tgm4 transactivation
Tagcloud (Difference) ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	adjacent androgen androgens antagonistic antagonistically ar btg1 cdca7l cdk6 chip confirming depends find htgp immunoprecipitation mapped position prostate proved publicly ra rar rare responsive restricted retinoic seq tgm4 transactivation
Tagcloud (Intersection) ?