HNRNPU and POU3F4

Number of citations of the paper that reports this interaction (PMID 9105675)
1

Data Source:
BioGRID (far western blotting)
HPRD (two hybrid, in vitro)

		HNRNPU	POU3F4
Gene Name		heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	POU class 3 homeobox 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cell Surface Membrane Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome	Nucleus
	Molecular Function	Core Promoter Binding DNA Binding RNA Binding Protein Binding ATP Binding Poly(A) RNA Binding	AT DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity
	Biological Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Gene Expression Circadian Regulation Of Gene Expression CRD-mediated MRNA Stabilization	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Sensory Perception Of Sound Forebrain Neuron Differentiation Cochlea Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: ACTB BTRC CASP3 CD5 CDKN2A CR2 ELL EP300 ERG GAS7 GRIN1 GRIN2D GTF2H1 HNRNPD HNRNPH3 IL7R KAT2B NDN NDRG1 NEDD4 NR3C1 PIN1 POLR2A POU3F4 PRMT1 PRPF40A PTPN11 SMN1 SREK1 STAU1 SYK TCERG1 WBP4 YAP1 ZNF689	4 interactors: HNRNPU POU3F1 POU3F2 POU3F3
Entrez ID		3192	5456
HPRD ID		04185	02076
Ensembl ID		ENSG00000153187	ENSG00000196767
Uniprot IDs		Q00839 Q96BA7	P49335
PDB IDs		1ZRJ
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Developmental Process Gene Expression Regulation Of Cell Cycle Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Viral Process MRNA Processing Multicellular Organismal Development Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process RNA Splicing Positive Regulation Of Viral Transcription Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process System Development MRNA Metabolic Process Positive Regulation Of Gene Expression Viral Process Positive Regulation Of Cellular Metabolic Process Signal Transduction RNA Processing Positive Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Regulation Of Cellular Process RNA Biosynthetic Process Cellular Response To Stimulus Cellular Nitrogen Compound Metabolic Process Anatomical Structure Morphogenesis Regulation Of Viral Process Transcription From RNA Polymerase II Promoter Regulation Of Viral Transcription Regulation Of T Cell Activation Signaling Transcription Initiation From RNA Polymerase II Promoter Cell Communication Regulation Of Metabolic Process Cellular Metabolic Process N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Surface Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process	Forebrain Ventricular Zone Progenitor Cell Division Myelination In Peripheral Nervous System Cell Proliferation In Forebrain Schwann Cell Development Forebrain Development Cerebral Cortex Radially Oriented Cell Migration Schwann Cell Differentiation Cerebral Cortex Cell Migration Telencephalon Cell Migration Forebrain Cell Migration Glial Cell Development Peripheral Nervous System Development Neural Precursor Cell Proliferation Brain Development Head Development Metanephric Macula Densa Development Metanephric DCT Cell Differentiation Myelination Axon Ensheathment Cerebral Cortex Development Central Nervous System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Neurohypophysis Development RNA Metabolic Process Glial Cell Differentiation Epithelium Development Pallium Development Cell Differentiation Gene Expression Metanephric Thick Ascending Limb Development Gliogenesis Positive Regulation Of Transcription, DNA-templated Epidermis Development CRD-mediated MRNA Stabilization Metanephric Ascending Thin Limb Development Telencephalon Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Metanephric Distal Convoluted Tubule Development Metanephric Loop Of Henle Development Nucleobase-containing Compound Metabolic Process Tissue Development Hypothalamus Cell Differentiation Metanephric Distal Tubule Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Cell Division
Tagcloud ?		17p13 1q21 1q44 2q23 2q31 agilent annotations asd autism backgrounds cgh cnv cnvs disabilities dissect encephalopathy epileptic exome expand hallux implicates infantile intellectual lissencephaly mbd5 microcephaly pafah1b1 pathogenicity spasms	abnormality accordingly acgh anomaly asian attempted causative counseling de deletions dfnx2 ear east etiologic homogeneity iii incomplete inheritance ip korean koreans look novo partition referral sanger siblings striking verify
Tagcloud (Difference) ?		17p13 1q21 1q44 2q23 2q31 agilent annotations asd autism backgrounds cgh cnv cnvs disabilities dissect encephalopathy epileptic exome expand hallux implicates infantile intellectual lissencephaly mbd5 microcephaly pafah1b1 pathogenicity spasms	abnormality accordingly acgh anomaly asian attempted causative counseling de deletions dfnx2 ear east etiologic homogeneity iii incomplete inheritance ip korean koreans look novo partition referral sanger siblings striking verify
Tagcloud (Intersection) ?