HMGA1 and OLA1

Number of citations of the paper that reports this interaction (PMID 18850631)
2

Data Source:
BioGRID (far western blotting)

		HMGA1	OLA1
Gene Name		high mobility group AT-hook 1	Obg-like ATPase 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytosol Focal Adhesion Senescence-associated Heterochromatin Focus	Nucleolus Cytoplasm Centrosome Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding AT DNA Binding DNA-(apurinic Or Apyrimidinic Site) Lyase Activity Protein Binding Transcription Factor Binding Enzyme Binding Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding 5'-deoxyribose-5-phosphate Lyase Activity	Protein Binding ATP Binding GTP Binding ATPase Activity Ribosome Binding Ribosomal Large Subunit Binding Metal Ion Binding
	Biological Process	DNA Catabolic Process, Endonucleolytic DNA Unwinding Involved In DNA Replication Base-excision Repair Nucleosome Disassembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Complex Assembly Negative Regulation Of Cell Proliferation Response To Virus Viral Process Negative Regulation Of Chromatin Silencing Senescence-associated Heterochromatin Focus Assembly Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Establishment Of Integrated Proviral Latency Oncogene-induced Cell Senescence Positive Regulation Of Cellular Senescence
Pathways		DNA Damage/Telomere Stress Induced Senescence Vpr-mediated nuclear import of PICs HIV Infection Cellular Senescence Host Interactions of HIV factors Integration of provirus Interactions of Vpr with host cellular proteins Early Phase of HIV Life Cycle Autointegration results in viral DNA circles HIV Life Cycle Formation of Senescence-Associated Heterochromatin Foci (SAHF) 2-LTR circle formation Integration of viral DNA into host genomic DNA APOBEC3G mediated resistance to HIV-1 infection
Drugs
Diseases
GWAS		Body mass index ( 20935630) Height ( 21998595 20881960 19396169 19343178 19893584 23563607 18391951 20397748 20189936)
Protein-Protein Interactions		60 interactors: ANXA1 ANXA2 APEX1 ATF2 CDK1 CEBPB CREBBP CSNK2A1 CSNK2A2 CWC27 DNAJC8 EIF2S2 ELF1 EWSR1 GTF2F2 HIPK2 HMGB1 HMGB2 HMGB3 HNRNPA1 HNRNPAB HNRNPD HNRNPDL HNRNPL HSPA1A IRF1 JUN KAT2B METAP2 NCL NFKB1 NFYA NPM1 OLA1 ORC6 PA2G4 PARP1 PCBP1 PCBP2 POU2F1 POU2F2 POU3F1 PPARG PPP1R8 PRKCA PRMT6 PSIP1 PTBP1 RARA RARG RCC1 RN7SK RNF4 RXRA SP1 SRF SSB SUFU SYNCRIP UPF2	6 interactors: ASCC2 BARD1 BRCA1 HMGA1 PRMT5 TUBG1
Entrez ID		3159	29789
HPRD ID		02829	15194
Ensembl ID		ENSG00000137309	ENSG00000138430
Uniprot IDs		P17096 Q5T6U8	Q9NTK5
PDB IDs		2EZD 2EZE 2EZF 2EZG	2OHF
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Gene Expression Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process MRNA Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Biosynthetic Process RNA Splicing, Via Transesterification Reactions Negative Regulation Of Gene Expression RNA Splicing Biosynthetic Process Negative Regulation Of Transcription, DNA-templated RNA Processing Transcription Initiation From RNA Polymerase II Promoter MRNA Processing Regulation Of Cell Cycle Viral Process Cell Differentiation Metabolic Process DNA-templated Transcription, Initiation Cellular Response To Organic Substance Developmental Process Regulation Of Cell Differentiation	Protein K6-linked Ubiquitination Negative Regulation Of Gene Expression Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation DNA Repair Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Negative Regulation Of MRNA 3'-end Processing Oncogene-induced Cell Senescence Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Senescence-associated Heterochromatin Focus Assembly Protein Polyubiquitination Cellular Response To DNA Damage Stimulus Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Senescence Regulation Of Cell Cycle Regulation Of Gene Expression, Epigenetic Cellular Response To Indole-3-methanol Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Centriole Replication Cell Cycle Process DNA Metabolic Process Negative Regulation Of Protein Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of Chromatin Silencing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Establishment Of Integrated Proviral Latency Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription DNA Replication Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Cellular Nitrogen Compound Metabolic Process Establishment Of Viral Latency Regulation Of Centriole Replication Histone H4-R3 Methylation Heterochromatin Assembly Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process Meiotic Spindle Organization
Tagcloud ?		arresting attribute augments bcl2 concomitantly e2 e6 evidences g0 galactosidase hmgb1 hpv16 htert kb linking mechanistic messaging papilloma re senescence senescent sensitizes shifted siha survivin sustaining tendency tnf tumorigenesis	1b acetate antioxidant biomarker comparative discovered dosing glatiramer highlighted ifnbeta ikbke insufficiency integrated knowledgebases mediators ms naive nd6 neuropathy nrf2 optic plausible pleiotropic preservation reduces relapsing remitting sclerosis signatures
Tagcloud (Difference) ?		arresting attribute augments bcl2 concomitantly e2 e6 evidences g0 galactosidase hmgb1 hpv16 htert kb linking mechanistic messaging papilloma re senescence senescent sensitizes shifted siha survivin sustaining tendency tnf tumorigenesis	1b acetate antioxidant biomarker comparative discovered dosing glatiramer highlighted ifnbeta ikbke insufficiency integrated knowledgebases mediators ms naive nd6 neuropathy nrf2 optic plausible pleiotropic preservation reduces relapsing remitting sclerosis signatures
Tagcloud (Intersection) ?