HIST1H1C and CTR9

Number of citations of the paper that reports this interaction (PMID 24360965)
0

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		HIST1H1C	CTR9
Gene Name		histone cluster 1, H1c	CTR9, Paf1/RNA polymerase II complex component
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus Nuclear Euchromatin	Cdc73/Paf1 Complex Nuclear Speck Transcriptionally Active Chromatin
	Molecular Function	Protein Binding Chromatin DNA Binding Poly(A) RNA Binding	RNA Polymerase II Core Binding Protein Binding SH2 Domain Binding
	Biological Process	Nucleosome Assembly Nucleosome Positioning	Negative Regulation Of Transcription From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Transcription, DNA-templated JAK-STAT Cascade Histone Monoubiquitination Wnt Signaling Pathway Stem Cell Maintenance Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2B Ubiquitination Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Interleukin-6-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Histone H3-K4 Trimethylation Positive Regulation Of Histone H3-K79 Methylation
Pathways		DNA Damage/Telomere Stress Induced Senescence Formation of Senescence-Associated Heterochromatin Foci (SAHF) Activation of DNA fragmentation factor Apoptosis induced DNA fragmentation Cellular Senescence Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: AEBP2 ASXL1 CDC73 CSNK2A2 CTNNB1 CTR9 CUL4A DDB1 F10 IL7R IRAK4 KPNA7 KPNB1 LEO1 NASP NCL NSD1 PAF1 PARP1 POLR2A PRKCA PRKDC PUF60 RBM39 RBX1 VHL WDR12 WDR5 YBX1	6 interactors: BLK CNTNAP2 HIST1H1C KMT2A SMAD9 TCEA1
Entrez ID		3006	9646
HPRD ID		07514	06717
Ensembl ID		ENSG00000187837	ENSG00000198730
Uniprot IDs		P16403	Q6PD62
PDB IDs
Enriched GO Terms of Interacting Partners?		Endodermal Cell Fate Commitment Protein Monoubiquitination Histone Monoubiquitination Positive Regulation Of Gene Expression Chromosome Organization Chromatin Modification Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Histone H2B Ubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Fate Commitment Involved In Formation Of Primary Germ Layer Regulation Of Nitrogen Compound Metabolic Process Chromatin Organization Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Endodermal Cell Differentiation Stem Cell Maintenance Histone Modification Negative Regulation Of Myeloid Cell Differentiation Histone Ubiquitination Positive Regulation Of Transcription, DNA-templated Regulation Of Myeloid Cell Differentiation Nitrogen Compound Metabolic Process Endoderm Formation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Protein Modification Process Stem Cell Development RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Wnt Signaling Pathway Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription, Elongation Endoderm Development Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Stem Cell Differentiation Gastrulation Regulation Of Cell Differentiation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Cell Differentiation RNA Metabolic Process Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter	Organ Development Positive Regulation Of Cellular Response To Drug Hemopoiesis Immune System Development Superior Temporal Gyrus Development Regulation Of Histone H3-K14 Acetylation Regulation Of Cellular Response To Drug Clustering Of Voltage-gated Potassium Channels System Development Regulation Of Response To Drug Multicellular Organismal Development Nucleosome Positioning Mullerian Duct Regression Anatomical Structure Development Protein Localization To Juxtaparanode Region Of Axon Neuronal Ion Channel Clustering Positive Regulation Of Transcription, DNA-templated Histone H3-K4 Trimethylation Regulation Of Histone H3-K9 Acetylation Developmental Process Histone H4-K16 Acetylation Thalamus Development Positive Regulation Of Histone H3-K4 Methylation Vocalization Behavior Striatum Development Positive Regulation Of Macromolecule Biosynthetic Process Anatomical Structure Regression Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Histone H3-K4 Methylation Subpallium Development Peptidyl-lysine Trimethylation
Tagcloud ?		allow arf cdkn2 chromosomal comprehensive correlates downregulation enable epigenetic epigenomic grades hox hypermethylation hypomethylation inactivates individualized meningioma meningiomas modifications object p14 pertaining profiling thorough timp3 tp73 tumorigenesis upregulation wnk2	antiparallel assembling assembly binds biochemical conserved coordinated detailed diverse elongation embryonic heterodimer histone identity leo1 maintenance modifications nucleosome octamer paf1 paf1c posttranscriptional recognition reveals scaffold shed sheet subcomplex tightly
Tagcloud (Difference) ?		allow arf cdkn2 chromosomal comprehensive correlates downregulation enable epigenetic epigenomic grades hox hypermethylation hypomethylation inactivates individualized meningioma meningiomas object p14 pertaining profiling thorough timp3 tp73 tumorigenesis upregulation wnk2	antiparallel assembling assembly binds biochemical conserved coordinated detailed diverse elongation embryonic heterodimer histone identity leo1 maintenance nucleosome octamer paf1 paf1c posttranscriptional recognition reveals scaffold shed sheet subcomplex tightly
Tagcloud (Intersection) ?		modifications