A1CF and APOBEC1

Number of citations of the paper that reports this interaction (PMID 10669759)
53

Data Source:
HPRD (in vitro, in vivo)

		A1CF	APOBEC1
Gene Name		APOBEC1 complementation factor	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Endoplasmic Reticulum Apolipoprotein B MRNA Editing Enzyme Complex	Nucleoplasm Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding AU-rich Element Binding
	Biological Process	MRNA Processing Gene Expression Cytidine To Uridine Editing MRNA Modification Protein Stabilization	RNA Processing MRNA Processing Lipid Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Response To Gamma Radiation Gene Expression Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Regulation Of Cell Proliferation Lipoprotein Biosynthetic Process Response To Drug Lipoprotein Transport Response To Ethanol MRNA Stabilization Response To Calcium Ion Defense Response To Virus DNA Demethylation Negative Regulation Of Methylation-dependent Chromatin Silencing
Pathways		mRNA Editing: C to U Conversion mRNA Editing Formation of the Editosome	mRNA Editing: C to U Conversion mRNA Editing Formation of the Editosome
Drugs
Diseases
GWAS		Urate levels ( 23263486)
Protein-Protein Interactions		9 interactors: APOBEC1 CELF2 FHL3 KHSRP REL SDPR SYNCRIP TNPO2 TRAF1	7 interactors: A1CF APOBEC2 BAG4 CELF2 DNAJB11 KPNA2 SYNCRIP
Entrez ID		29974	339
HPRD ID		10627	02531
Ensembl ID		ENSG00000148584	ENSG00000111701
Uniprot IDs		B4E1E3 Q9NQ94	P41238
PDB IDs		2CPD
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Processing MRNA Stabilization RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Stability Regulation Of RNA Stability RNA Splicing Cytidine To Uridine Editing Negative Regulation Of Methylation-dependent Chromatin Silencing Regulation Of Methylation-dependent Chromatin Silencing CRD-mediated MRNA Stabilization RNA Metabolic Process Base Conversion Or Substitution Editing Negative Regulation Of Chromatin Silencing Gene Expression MRNA Splicing, Via Spliceosome Cytidine Deamination Regulation Of MiRNA Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process DNA Demethylation MRNA Modification Positive Regulation Of Gene Expression, Epigenetic Pyrimidine Nucleoside Catabolic Process Lipoprotein Transport Regulation Of Gene Silencing Defense Response	MRNA Modification MRNA Metabolic Process MRNA Processing RNA Modification RNA Processing Negative Regulation Of MRNA Modification Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Cytokine Stimulus Cellular Nitrogen Compound Metabolic Process Cytidine To Uridine Editing RNA Metabolic Process Response To Cytokine Nitrogen Compound Metabolic Process Cellular Response To Organic Substance CRD-mediated MRNA Stabilization MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Base Conversion Or Substitution Editing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cytidine Deamination Cellular Metabolic Process Protein Folding Intracellular MRNA Localization Positive Regulation Of Fibroblast Migration Response To Organic Substance RNA Splicing Regulation Of Metabolic Process DNA Demethylation Pyrimidine Nucleoside Catabolic Process NLS-bearing Protein Import Into Nucleus Ruffle Assembly Posttranscriptional Regulation Of Gene Expression Cellular Response To Epidermal Growth Factor Stimulus MRNA Stabilization Response To Epidermal Growth Factor Regulation Of Fibroblast Migration Viral Process Gene Expression Ruffle Organization MRNA Splice Site Selection Positive Regulation Of Stress Fiber Assembly
Tagcloud ?		apo apob causality conclusionsincreased crystals editing europeans gout hu immunosorbant introductiongout inverted mark10 mark3 mark6 markmol markori markx methodsnew monosodium msu normouricemia nu polynesian polynesians resultsincreased trended urate vldl	aid apolipoprotein atherosclerosis atherosclerotic causal coincident crosses dissecting dyslipidemia editing founder genotyped hampers haplotypes hfca hidden inbred informative mapping markov multiparental outbred qtl reconstructed renders trait triglyceride triglycerides
Tagcloud (Difference) ?		apo causality conclusionsincreased crystals europeans gout hu immunosorbant introductiongout inverted mark10 mark3 mark6 markmol markori markx methodsnew monosodium msu normouricemia nu polynesian polynesians resultsincreased trended urate vldl	aid apolipoprotein atherosclerosis atherosclerotic causal coincident crosses dissecting dyslipidemia founder genotyped hampers haplotypes hfca hidden inbred informative mapping markov multiparental outbred qtl reconstructed renders trait triglyceride triglycerides
Tagcloud (Intersection) ?		apob editing