UTP20 and PPP1R26

Number of citations of the paper that reports this interaction (PMID 16053918)
2

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		UTP20	PPP1R26
Gene Name		UTP20, small subunit (SSU) processome component, homolog (yeast)	protein phosphatase 1, regulatory subunit 26
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm 90S Preribosome Preribosome, Small Subunit Precursor Small-subunit Processome	Nucleoplasm Nucleolus
	Molecular Function	Protein Binding Poly(A) RNA Binding	Protein Phosphatase Inhibitor Activity Protein Binding Phosphatase Binding
	Biological Process	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Negative Regulation Of Cell Proliferation	Negative Regulation Of Phosphatase Activity
Pathways
Drugs
Diseases
GWAS		Brain structure (hippocampal volume) ( 20197096)
Protein-Protein Interactions		1 interactors: PPP1R26	2 interactors: PPP1CA UTP20
Entrez ID		27340	9858
HPRD ID		09928	11099
Ensembl ID		ENSG00000120800	ENSG00000196422
Uniprot IDs		O75691	Q5T8A7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Phosphatase Activity Negative Regulation Of Dephosphorylation Regulation Of Phosphatase Activity Regulation Of Dephosphorylation	Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RNA 5'-end Processing Regulation Of Glycogen Catabolic Process Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Maturation Of SSU-rRNA Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Glycogen Metabolic Process Ribosomal Small Subunit Biogenesis Glycogen Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Regulation Of Generation Of Precursor Metabolites And Energy Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Triglyceride Metabolic Process Regulation Of Circadian Rhythm Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Glucose Metabolic Process Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus RNA Phosphodiester Bond Hydrolysis RRNA Processing RRNA Metabolic Process Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Lipid Catabolic Process Regulation Of Carbohydrate Metabolic Process Circadian Rhythm Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Ribosome Biogenesis Response To Transforming Growth Factor Beta Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Branching Morphogenesis Of An Epithelial Tube Cellular Carbohydrate Metabolic Process Morphogenesis Of A Branching Epithelium
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