BLOC1S6 and SKA1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		BLOC1S6	SKA1
Gene Name		biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	spindle and kinetochore associated complex subunit 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Endosome Cytosol Extrinsic Component Of Membrane Transport Vesicle BLOC-1 Complex SNARE Complex	Condensed Chromosome Outer Kinetochore Cytosol Spindle Microtubule Microtubule Cytoskeleton
	Molecular Function	Protein Binding Syntaxin Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding	Protein Binding Microtubule Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Blood Coagulation Anterograde Axon Cargo Transport Synaptic Vesicle Docking Melanocyte Differentiation Neuron Projection Development Melanosome Transport Melanosome Organization Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Endosome To Melanosome Transport Anterograde Synaptic Vesicle Transport Positive Regulation Of Pigment Cell Differentiation Membrane Organization Membrane Fusion	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Regulation Of Microtubule Polymerization Or Depolymerization Cell Division
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		38 interactors: ABI2 AGGF1 ANK1 APP BLOC1S1 BLOC1S2 BLOC1S4 CCDC136 CCDC22 CCDC53 CCHCR1 CDK5R1 CORO6 DCTN2 DTNBP1 EPS8 EXOC8 HAUS1 IFT20 KRT13 LURAP1 MED21 NDC80 NDN NUP62 OLFM2 PLEKHA5 PLEKHF2 RABGEF1 SKA1 SLC4A1 SMN2 SNAPIN STX11 STX12 SYCE3 TPM3 WDYHV1	7 interactors: AURKB BLOC1S6 LINC00521 NDC80 SKA2 SPC24 SYCE1
Entrez ID		26258	220134
HPRD ID		16055	12689
Ensembl ID		ENSG00000104164	ENSG00000154839
Uniprot IDs		B3KY40 Q9UL45	Q96BD8
PDB IDs			4AJ5
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Establishment Of Localization In Cell Axon Cargo Transport Melanosome Organization Pigment Granule Organization Organelle Organization Cellular Pigmentation Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Organelle Localization Synaptic Vesicle Transport Movement Of Cell Or Subcellular Component Establishment Of Vesicle Localization Intracellular Transport Pigmentation Vesicle Organization Establishment Of Organelle Localization Vesicle Localization Membrane Organization Neuron Development Microtubule-based Process Neuron Projection Development Platelet Dense Granule Organization Microtubule-based Movement Cytoskeleton Organization Neuron Differentiation Cell Projection Organization Vesicle-mediated Transport Protein Localization Protein Transport Establishment Of Protein Localization Cell Development Post-Golgi Vesicle-mediated Transport Generation Of Neurons Cellular Protein Localization Neurogenesis Neuron Recognition Secretory Granule Organization Transport Endomembrane System Organization Golgi Vesicle Transport Vesicle Fusion Nervous System Development Mitotic Nuclear Division Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Exocytosis Organelle Fusion	Cell Division Chromosome Segregation Mitotic Nuclear Division Cell Cycle Process Attachment Of Spindle Microtubules To Kinetochore Cell Cycle Organelle Organization Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Spindle Organization Microtubule Anchoring Regulation Of Microtubule Polymerization Or Depolymerization Spindle Organization Regulation Of Microtubule Cytoskeleton Organization Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Microtubule-based Process Regulation Of Microtubule-based Process Histone H3-S28 Phosphorylation Spindle Stabilization Attachment Of Mitotic Spindle Microtubules To Kinetochore Abscission Secretion Of Lysosomal Enzymes Chromosome Organization Mitotic Spindle Midzone Assembly Cleavage Furrow Formation Mitotic Spindle Elongation Endosome To Melanosome Transport Pigment Granule Maturation Synaptic Vesicle Docking Protein Localization To Kinetochore Negative Regulation Of Cytokinesis Cellular Pigment Accumulation Spindle Midzone Assembly Establishment Of Organelle Localization Protein Localization To Chromosome, Centromeric Region Negative Regulation Of B Cell Apoptotic Process Positive Regulation Of Pigment Cell Differentiation Positive Regulation Of Developmental Pigmentation Histone-serine Phosphorylation Organelle Localization Regulation Of B Cell Apoptotic Process Anterograde Synaptic Vesicle Transport Microtubule Cytoskeleton Organization Mitotic Spindle Assembly Melanosome Organization Pigment Granule Organization Synaptonemal Complex Assembly Regulation Of Developmental Pigmentation
Tagcloud ?			2gammanul amo1 aspm aurkb birc5 bortezomib ccnb1 cd138 cdc2 cdc25c cenpe clonogenic downregulates epc1 hist jjn3 kifs kms myeloma possessing psma5 rpmi shi sp sps top2a ube2d3 ube3c vx
Tagcloud (Difference) ?			2gammanul amo1 aspm aurkb birc5 bortezomib ccnb1 cd138 cdc2 cdc25c cenpe clonogenic downregulates epc1 hist jjn3 kifs kms myeloma possessing psma5 rpmi shi sp sps top2a ube2d3 ube3c vx
Tagcloud (Intersection) ?