B3GAT3 and SEC22B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		B3GAT3	SEC22B
Gene Name		beta-1,3-glucuronyltransferase 3	SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome
	Molecular Function	Protein Binding Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase Activity Glucuronosyltransferase Activity Metal Ion Binding Protein Phosphatase Activator Activity	Protein Binding Syntaxin Binding
	Biological Process	Carbohydrate Metabolic Process Glycosaminoglycan Biosynthetic Process Protein Glycosylation Pathogenesis Heparan Sulfate Proteoglycan Biosynthetic Process Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Positive Regulation Of Catalytic Activity Small Molecule Metabolic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Intracellular Protein Transport	ER To Golgi Vesicle-mediated Transport Protein Transport Regulation Of Organelle Organization Positive Regulation Of Protein Catabolic Process
Pathways		MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Heparan sulfate/heparin (HS-GAG) metabolism Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Defective CHST6 causes MCDC1 Glycogen storage diseases MPS IIID - Sanfilippo syndrome D A tetrasaccharide linker sequence is required for GAG synthesis MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B Defective CHSY1 causes TPBS MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs		Udp-Glucuronic Acid Uridine-5\'-Diphosphate
Diseases
GWAS
Protein-Protein Interactions		2 interactors: HNRNPD SEC22B	2 interactors: B3GAT3 STX5
Entrez ID		26229	9554
HPRD ID		07564	04939
Ensembl ID		ENSG00000149541
Uniprot IDs		B7ZAB3 O94766	O75396
PDB IDs		1FGG 1KWS 3CU0	2NUP 2NUT 3EGD 3EGX
Enriched GO Terms of Interacting Partners?		Circadian Regulation Of Translation	Golgi Disassembly Golgi Inheritance Regulation Of Golgi Organization Vesicle Fusion With Golgi Apparatus Early Endosome To Golgi Transport Dermatan Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Metabolic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Heparan Sulfate Proteoglycan Biosynthetic Process Heparan Sulfate Proteoglycan Metabolic Process Organelle Disassembly Vesicle Fusion Proteoglycan Biosynthetic Process Chondroitin Sulfate Metabolic Process Retrograde Transport, Endosome To Golgi Organelle Fusion Golgi Organization Vesicle Docking Membrane Docking Glycosaminoglycan Biosynthetic Process ER To Golgi Vesicle-mediated Transport Proteoglycan Metabolic Process Membrane Fusion Positive Regulation Of Intracellular Protein Transport
Tagcloud ?			bundle coat compete copii dissociates ejected enclosed facilitates golgi golgin gtpases membrin monomeric opposed p115 preferences prefusion proceed rab rbet1 snare snarepin snares stably stemmed syntaxin tether tethering vesicles
Tagcloud (Difference) ?			bundle coat compete copii dissociates ejected enclosed facilitates golgi golgin gtpases membrin monomeric opposed p115 preferences prefusion proceed rab rbet1 snare snarepin snares stably stemmed syntaxin tether tethering vesicles
Tagcloud (Intersection) ?