POT1 and BCAS2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		POT1	BCAS2
Gene Name		protection of telomeres 1	breast carcinoma amplified sequence 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm DNA Replication Factor A Complex Spliceosomal Complex Nucleolus Cell Junction
	Molecular Function	Protein Binding Telomerase Inhibitor Activity DEAD/H-box RNA Helicase Binding Single-stranded Telomeric DNA Binding	Protein Binding
	Biological Process	Telomere Maintenance Telomere Maintenance Via Telomerase Telomere Capping Telomere Formation Via Telomerase Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase DNA Duplex Unwinding Positive Regulation Of Helicase Activity Positive Regulation Of Telomerase Activity Negative Regulation Of Telomerase Activity Positive Regulation Of DNA Strand Elongation	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression
Pathways		Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		166 interactors: ACD ACOT7 ACTB ACTN4 ACY1 AFAP1L2 AHCY AHNAK AIPL1 ALDH1A1 ALDH3A1 AMPD2 ANKMY2 ANXA2 ANXA4 APPL2 ARHGDIA ARID3B ARRB1 BAG3 BCAS2 BIN2 C15orf57 C2orf74 CALD1 CAMK1D CCDC9 CCM2 CFL1 CFL2 CKB CLIC3 CNST CORO1A COX6A2 CPNE3 CPPED1 CRK CRYGS CSNK2B CYP4F11 DBN1 DBNL DCX DDX19B DNPH1 DOK2 DPP3 DPYSL3 ECI1 EEF1D EIF3G EIF4B ENO2 ENSA EPB41L1 EVL FAM131B FBP1 FES GAMT GAPDH GAS2L1 GFPT2 GNMT GPA33 GPR52 GRN HAAO HLCS HMOX1 HNMT HOXA3 HSP90AB1 HSPA1A IFRD2 IL1RN ISYNA1 IVL KHDRBS1 KIAA1191 KRT18 LAMC3 LASP1 LDHA LDHB MADD MAGEA4 MAP4 MAP4K2 MAP7 MDM2 MICA MT1X MVK MVP MYO5C NAP1L1 NCDN NOL3 NUDC NUDCD2 NXNL1 PACSIN1 PACSIN2 PAGE2 PAGE5 PAK4 PALM PCP4 PDE1B PDLIM2 PEX5 PFKP PGLS PGM1 PGM2 PHYHD1 PHYKPL PIPOX PRMT7 PROSER2 RBKS RECQL4 RGS14 RIF1 RPAP1 RPSA RTN4 SARS SBDS SERTAD1 SH3BP1 SNCG STIP1 STUB1 SULT1B1 SULT1C2 SULT4A1 SYAP1 TAGLN TBCD TERF1 TERF2 TINF2 TMSB10 TMSB4Y TNKS TOMM34 TPI1 TPP1 TRIM16 TRIP10 TUBB2A TUBB4B TWF2 WIBG WIPI2 XAGE2 YWHAE YWHAG ZBED2 ZBTB49 ZFP36L1 ZNF32 ZNF790	18 interactors: AIMP2 BLK CDC5L EP300 ESR1 ESR2 GOLGA2 HGS IKZF3 KRT40 PGR POT1 PPARG PRPF19 SF1 TCF4 TXNRD2 UBC
Entrez ID		25913	10286
HPRD ID		07572	05777
Ensembl ID		ENSG00000128513	ENSG00000116752
Uniprot IDs		A8MTK3 Q5MJ33 Q9NUX5	B2R7W3 O75934
PDB IDs		1XJV 3KJO 3KJP
Enriched GO Terms of Interacting Partners?		Protein Localization To Chromosome, Telomeric Region Regulation Of Telomere Maintenance Regulation Of Cellular Component Organization Regulation Of Telomere Maintenance Via Telomerase Organelle Organization Negative Regulation Of Telomere Maintenance Small Molecule Metabolic Process Cellular Component Assembly Regulation Of Organelle Organization Negative Regulation Of Telomere Maintenance Via Telomerase Cytoskeleton Organization Organic Acid Metabolic Process Response To Stimulus Catabolic Process Regulation Of Binding Cellular Process Carboxylic Acid Metabolic Process Cofactor Metabolic Process Protein Localization To Chromosome Cellular Response To Stimulus Actin Filament Organization Protection From Non-homologous End Joining At Telomere Response To Abiotic Stimulus Carbohydrate Catabolic Process Carbohydrate Biosynthetic Process Protein Localization Telomere Assembly Telomere Capping Positive Regulation Of Organelle Organization Nervous System Development Cellular Protein Localization Response To Stress Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Telomere Maintenance Cellular Metabolic Process Pyruvate Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Regulation Of Cytoskeleton Organization Negative Regulation Of DNA Replication Response To External Stimulus Actin Cytoskeleton Organization Glycolytic Process Cellular Localization Regulation Of Protein Metabolic Process Gluconeogenesis Sequestering Of Actin Monomers Regulation Of Neuron Projection Development Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Developmental Process	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Regulation Of Cell Proliferation Hormone-mediated Signaling Pathway Rhythmic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To Steroid Hormone Stimulus RNA Metabolic Process Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Response To Steroid Hormone Ovulation Cycle Process Transcription, DNA-templated Tissue Development Reproductive Structure Development Reproductive System Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Female Gonad Development Biosynthetic Process Ovulation Cycle Transcription From RNA Polymerase II Promoter Development Of Primary Female Sexual Characteristics Regulation Of Transcription From RNA Polymerase II Promoter Sex Differentiation Cellular Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Response To Hormone Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Epithelium Development Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Organic Cyclic Compound Developmental Process Involved In Reproduction Cellular Response To Lipid Genitalia Development Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Negative Regulation Of Telomerase Activity Regulation Of Gene Expression
Tagcloud ?		0mug celltiter chemosensitivity ddp downregulate fluorescein formerly gastroesophageal gc iodide isothiocyanate junction n87 nci oncological oxa oxaliplatin performing pip platinum propodium ptop telomere telomeric tint1 tpp1 trastuzumab trf2 trf2ip	amplified ar assay carcinoma characterise characterised correlation degraded gst hsp90 immunohistochemical immunoprecipitation interacting lncap luciferase manners mtt p53 pca propose prostate proteasome pull regulator specimens stabilise stabilised suppressed upregulation
Tagcloud (Difference) ?		0mug celltiter chemosensitivity ddp downregulate fluorescein formerly gastroesophageal gc iodide isothiocyanate junction n87 nci oncological oxa oxaliplatin performing pip platinum propodium ptop telomere telomeric tint1 tpp1 trastuzumab trf2 trf2ip	amplified ar assay carcinoma characterise characterised correlation degraded gst hsp90 immunohistochemical immunoprecipitation interacting lncap luciferase manners mtt p53 pca propose prostate proteasome pull regulator specimens stabilise stabilised suppressed upregulation
Tagcloud (Intersection) ?