BRMS1 and SMARCE1

Number of citations of the paper that reports this interaction (PMID 16919237)
26

Data Source:
HPRD (two hybrid, in vivo)

		BRMS1	SMARCE1
Gene Name		breast cancer metastasis suppressor 1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex	Nuclear Chromosome Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex Transcriptional Repressor Complex Protein Complex NpBAF Complex NBAF Complex
	Molecular Function	Histone Deacetylase Activity Protein Binding Histone Deacetylase Binding NF-kappaB Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding N-acetyltransferase Activity Ligand-dependent Nuclear Receptor Binding Nucleosomal DNA Binding Protein N-terminus Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Metabolic Process ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones	Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		36 interactors: APP ARID4A BRMS1L CEP70 DNAJB1 DNAJB6 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 ING1 KPNA5 LINC00152 LRIF1 NMI PFDN5 RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNX6 SPOP SUDS3 TAF1 UBE2D1	63 interactors: AMOTL2 AR ARID2 BAZ1B BRMS1 CCDC136 CCDC172 CDR2 CEP170P1 CEP63 CEP70 DISC1 EPS8 ESR1 ESR2 EXOC7 GATA1 GOLGA2 ING5 ITCH JAKMIP2 KIFC3 KLF1 KRT15 KRT31 KRT40 KRTAP10-9 MDM2 MED4 MEOX2 MIPOL1 MRFAP1L1 MTUS2 NBPF22P NCOA1 NCOA2 NCOA3 NOTCH2NL NR0B2 NR3C1 NUP62 PGR PRMT5 RALBP1 RARA RCOR1 RELB RINT1 SIN3A SIN3B SMAD1 SMARCA4 SPAG5 SRC STX11 SYCE1 TFE3 TFIP11 TNIK TRIM54 TRIP10 TXLNA USHBP1
Entrez ID		25855	6605
HPRD ID		05879	04382
Ensembl ID		ENSG00000174744	ENSG00000073584
Uniprot IDs		G5E9I4 Q9HCU9	Q969G3
PDB IDs		2XUS 4AUV
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Modification Histone Deacetylation Negative Regulation Of Transcription, DNA-templated Protein Deacetylation Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Histone H3-K9 Modification Chromosome Organization Negative Regulation Of Biosynthetic Process Histone Modification Negative Regulation Of Cellular Metabolic Process Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Histone H4 Deacetylation Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Histone H3 Deacetylation Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of Gene Expression Cellular Response To Heat Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Chromatin Remodeling Positive Regulation Of Macromolecule Biosynthetic Process Response To Heat Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process ATP-dependent Chromatin Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process	Intracellular Steroid Hormone Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Transcription, DNA-templated Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Organelle Organization Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Modification Transcription From RNA Polymerase II Promoter Chromosome Organization RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Hormone Stimulus Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Response To Steroid Hormone Stimulus Hormone-mediated Signaling Pathway Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Histone Modification Negative Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Hormone Gland Development Cellular Response To Organic Cyclic Compound Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Initiation Negative Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Steroid Hormone Negative Regulation Of Nucleic Acid-templated Transcription Organ Development Negative Regulation Of RNA Biosynthetic Process Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Regulation Of Signal Transduction
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic	acetylase aldh1a3 belonging bipotent cbx6 ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico subpopulations trithorax
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic	acetylase aldh1a3 belonging bipotent cbx6 ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico subpopulations trithorax
Tagcloud (Intersection) ?