GABPA and GABPB1

Number of citations of the paper that reports this interaction (PMID 9461436)
77

Data Source:
HPRD (in vitro, in vivo)

		GABPA	GABPB1
Gene Name		GA binding protein transcription factor, alpha subunit 60kDa	GA binding protein transcription factor, beta subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Utero Embryonic Development Transcription From RNA Polymerase II Promoter Organelle Organization Mitochondrion Organization Cell Differentiation Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Mitochondrion Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Organelle biogenesis and maintenance Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APP ATF1 CREBBP EP300 GABPB1 HCFC1 MED1 PINX1 SP1 SP3	23 interactors: ATF1 BAI2 CIC FAM90A1 FANCG GABPA HCFC1 IL16 LMO1 LMO3 LMO4 MAGEB18 POGZ RBM11 RSPH14 RYBP SNRPA SNRPB2 TDRD7 TRAF2 USO1 YAF2 ZDHHC17
Entrez ID		2551	2553
HPRD ID		11793	15975
Ensembl ID		ENSG00000154727	ENSG00000104064
Uniprot IDs		A8IE48 Q06546 Q8IYS3	Q06547
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Enucleate Erythrocyte Differentiation Positive Regulation Of Cellular Metabolic Process Megakaryocyte Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process N-terminal Peptidyl-lysine Acetylation Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Immune System Process Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Homeostatic Process Positive Regulation By Host Of Viral Transcription Embryonic Process Involved In Female Pregnancy Negative Regulation Of Transcription From RNA Polymerase II Promoter N-terminal Protein Amino Acid Acetylation Regulation Of Metabolic Process Erythrocyte Differentiation Histone Acetylation Erythrocyte Homeostasis Embryonic Placenta Development Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Myeloid Cell Homeostasis Monocyte Differentiation Notch Signaling Pathway	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Release From Viral Latency Golgi Vesicle Docking Regulation Of Metabolic Process Toll-like Receptor 4 Signaling Pathway Biosynthetic Process Cellular Protein Complex Assembly RNA Splicing Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Toll-like Receptor Signaling Pathway Mitochondrion Organization Negative Regulation Of Megakaryocyte Differentiation MRNA Processing Transcription From RNA Polymerase II Promoter Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction
Tagcloud ?		annotation assigned bindings cistrome consensus enriched examines expresses foxa2 generates hepatic hre implying isoforms livers motifs principle ra rar rara raralpha rarb rarbeta redundant responsiveness sp1 stores tca uncovered	arsenic as1 cadmium capabilities cdkn2b chemical coding cycloheximide ethical flj33630 hipscs ideal indicators linc00152 linc0541471 lncrnas mir22hg mrnas peroxide pervasive pluripotent possess renewal responded rnas stresses surrogate toxicological v2
Tagcloud (Difference) ?		annotation assigned bindings cistrome consensus enriched examines expresses foxa2 generates hepatic hre implying isoforms livers motifs principle ra rar rara raralpha rarb rarbeta redundant responsiveness sp1 stores tca uncovered	arsenic as1 cadmium capabilities cdkn2b chemical coding cycloheximide ethical flj33630 hipscs ideal indicators linc00152 linc0541471 lncrnas mir22hg mrnas peroxide pervasive pluripotent possess renewal responded rnas stresses surrogate toxicological v2
Tagcloud (Intersection) ?