XRCC6 and ARAP1

  • Number of citations of the paper that reports this interaction (PMID 16169070)
  • 531
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)
  • HPRD (two hybrid)

XRCC6

ARAP1

Gene Name X-ray repair complementing defective repair in Chinese hamster cells 6 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Fasting glucose-related traits (interaction with BMI) ( 22581228)
  • Proinsulin levels ( 21873549)
  • Rheumatoid arthritis ( 22446963)
Protein-Protein Interactions 126 interactors: ABCD4 ABL1 ACD ADCY7 ANXA1 APEX1 AR ARAP1 ATP6V1E1 BARD1 BAZ1A BTG1 CAPN11 CBX5 CCNA1 CCT3 CD40 CDCA5 CDK2 CDKN1A CEBPA CENPU CHAF1A CHEK1 CLTC CLU CMTM6 COIL COPB1 CREBBP CSNK2A1 CTBP2 DLX2 DNTT EFNA1 EGFR EID1 ELF3 EP300 EPS8 FMNL1 GAL3ST4 GSE1 GZMA GZMB H2AFX HERPUD1 HMGA2 HN1L HOXB7 HOXC4 HOXD4 HSF1 HTT ILVBL KAT2A KAT2B KIAA0408 LIG3 MAP2K5 MAP4K2 MAPK8 MRE11A MSX2 NAA15 NCF4 NCL NCOA6 NHP2L1 NIT1 NOTCH1 PAEP PAFAH1B3 PARP1 PCNA PDK1 PDPK1 PDX1 PECAM1 PGAM1 PGR PIN1 PLGRKT PNRC2 POR POU2F1 POU2F2 PRKDC PRPF40A PTTG1 QRSL1 RASA1 RBBP4 RGS2 RNF146 RPLP1 RPS10 RRAS2 RUNX2 SDHC SEP15 SERPINA2 SERPINB9 SGOL1 SIRT3 SKIL SMAD3 SMAD7 SNTA1 SPARC TAC1 TADA3 TBCD TCF4 TERF2 TERF2IP TERT TP53 VAV1 VBP1 WBP4 WRN XRCC5 XRCC6BP1 YWHAZ ZNF512B 13 interactors: APP ARIH2 ARPC3 FGFR3 INPP5D KCTD12 PSD3 SH3KBP1 TAB1 TES TP53BP1 WAPAL XRCC6
Entrez ID 2547 116985
HPRD ID 01071 09440
Ensembl ID ENSG00000196419 ENSG00000186635
Uniprot IDs B1AHC8 B1AHC9 P12956 E7EU13 Q96P48
PDB IDs 1JEQ 1JEY 1JJR 3RZX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
brca2  cellularity  cg  chance  copyright  cytopenia  genesis  genotype  genotyped  gg  heterozygote  hypercellular  john  karyotype  lig4  ltd  normocellular  polymorphism  polymorphisms  rad51  rs1801320  rs1805388  rs2267437  rs3835  rs4793191  rs9567623  sons  wiley  xrcc5 
abl1  annotates  bcr  casl  centd2  compensate  crk  crki  crkii  directionality  dok  dok1  dok2  gab2  gtpase  gtpases  hef1  layered  lrrk1  lrrk2  modular  nedd9  paralog  pleiotropic  pragmin  rhoa  sgk223  shc1  wise 
Tagcloud (Difference) ?
brca2  cellularity  cg  chance  copyright  cytopenia  genesis  genotype  genotyped  gg  heterozygote  hypercellular  john  karyotype  lig4  ltd  normocellular  polymorphism  polymorphisms  rad51  rs1801320  rs1805388  rs2267437  rs3835  rs4793191  rs9567623  sons  wiley  xrcc5 
abl1  annotates  bcr  casl  centd2  compensate  crk  crki  crkii  directionality  dok  dok1  dok2  gab2  gtpase  gtpases  hef1  layered  lrrk1  lrrk2  modular  nedd9  paralog  pleiotropic  pragmin  rhoa  sgk223  shc1  wise 
Tagcloud (Intersection) ?