FTH1 and ELL3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FTH1	ELL3
Gene Name		ferritin, heavy polypeptide 1	elongation factor RNA polymerase II-like 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Cytosol Intracellular Ferritin Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Transcription Elongation Factor Complex
	Molecular Function	Ferroxidase Activity Iron Ion Binding Protein Binding Ferric Iron Binding	Enhancer Binding
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Intracellular Sequestering Of Iron Ion Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Immune Response Negative Regulation Of Cell Proliferation Negative Regulation Of Fibroblast Proliferation Transmembrane Transport Oxidation-reduction Process Membrane Organization	DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Spermatogenesis Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of DNA-templated Transcription, Elongation SnRNA Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Stem Cell Differentiation Positive Regulation Of Neurogenesis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Iron uptake and transport Golgi Associated Vesicle Biogenesis Scavenging by Class A Receptors trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs		Iron Dextran
Diseases
GWAS		Estradiol levels ( 22675492) Phospholipid levels (plasma) ( 21829377)
Protein-Protein Interactions		31 interactors: BRD7 CD99 CDC16 CDC25A CRMP1 CSF3R CSNK2B DAXX ELL3 FTL FXR2 GOLM1 GRB2 KPNA2 LBP MAX MYL3 NR1I3 NR3C1 NR5A2 PACSIN1 PIAS4 SDCBP SOX5 SPP1 TICAM2 TOLLIP TRAF4 UBR1 WDYHV1 YWHAE	1 interactors: FTH1
Entrez ID		2495	80237
HPRD ID		00615	10933
Ensembl ID		ENSG00000167996	ENSG00000128886
Uniprot IDs		P02794	Q9HB65
PDB IDs		1FHA 2CEI 2CHI 2CIH 2CLU 2CN6 2CN7 2FHA 2IU2 2Z6M 3AJO 3AJP 3AJQ 3ERZ 3ES3 4DYX 4DYY 4DYZ 4DZ0
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Response To Organic Substance Positive Regulation Of Metabolic Process Cellular Response To Stimulus Regulation Of Metabolic Process Chemotaxis Positive Regulation Of Signal Transduction Hormone-mediated Signaling Pathway Response To Stimulus Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Cell Communication Regulation Of Protein Metabolic Process System Development Movement Of Cell Or Subcellular Component Cellular Response To Hormone Stimulus Regulation Of Signal Transduction Generation Of Neurons Anatomical Structure Development Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Toll-like Receptor Signaling Pathway Locomotion Positive Regulation Of Protein Sumoylation Signaling Response To Hormone Neurogenesis Cellular Response To Lipid Leukocyte Migration Signal Transduction Regulation Of Signaling Steroid Hormone Mediated Signaling Pathway Multicellular Organismal Development Regulation Of Protein Sumoylation Response To External Stimulus Leukocyte Chemotaxis Regulation Of Cellular Process Positive Regulation Of Cellular Protein Metabolic Process Developmental Process Positive Regulation Of JNK Cascade Cell Migration Response To Lipid Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Transcription From RNA Polymerase II Promoter Cell Motility Negative Regulation Of Gene Expression	Intracellular Sequestering Of Iron Ion Sequestering Of Metal Ion Negative Regulation Of Fibroblast Proliferation Iron Ion Transport Cellular Iron Ion Homeostasis Post-Golgi Vesicle-mediated Transport Regulation Of Fibroblast Proliferation Iron Ion Homeostasis Transition Metal Ion Homeostasis Maintenance Of Location In Cell Golgi Vesicle Transport Receptor-mediated Endocytosis
Tagcloud ?		aggravating anxa1 banks bedside confidently cons ftl gliosis got2 immunochemical infarct infarcted infarcts itraq lagging leak malate mdh2 mortem plex pros proteome proteomics putamen shuttle slc25a11 slc25a12 tca vim
Tagcloud (Difference) ?		aggravating anxa1 banks bedside confidently cons ftl gliosis got2 immunochemical infarct infarcted infarcts itraq lagging leak malate mdh2 mortem plex pros proteome proteomics putamen shuttle slc25a11 slc25a12 tca vim
Tagcloud (Intersection) ?