TFIP11 and CCDC121

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TFIP11	CCDC121
Gene Name		tuftelin interacting protein 11	coiled-coil domain containing 121
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Spliceosomal Complex Cytoplasm Nuclear Speck U2-type Post-mRNA Release Spliceosomal Complex Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding
	Biological Process	Spliceosomal Complex Disassembly MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated RNA Processing Biomineral Tissue Development
Pathways
Drugs
Diseases
GWAS			Waist Circumference - Triglycerides (WC-TG) ( 21386085)
Protein-Protein Interactions		102 interactors: ABI2 ADCK3 AIMP2 ALS2CR11 ANKRD11 ARMCX1 ARNT2 ATP5O BMF C1orf109 C6orf165 CARD9 CCDC116 CCDC121 CCDC146 CCDC151 CCDC42 CCDC68 CCHCR1 CCND3 CCNG1 CCNL1 CCP110 CENPU CEP57 CEP57L1 COX5B DGCR6 DISC1 EIF3A FAM13C FAM156A FAM161A FAM50B GCC1 GEM GNG4 GOLGA1 GPS2 HAUS1 HMG20B HOOK1 IKBIP IMP3 KANSL1 KRT20 KRT6A KRT6B KRT6C KRT8 LATS1 LCA5L LENG1 LIN37 LINC00238 LMO1 LMO4 LSP1P3 METTL17 MTFR2 NDC80 NDE1 NDN NFU1 OIP5 PBX4 PDE4DIP POLL PPP1R18 PRPF31 RCOR3 RHNO1 RRP7A S100P SAP30BP SFR1 SH2D4A SH3GLB1 SMARCE1 SNRPB SNW1 SNX20 SSX2IP STRN TCAF1 TFPT THAP7 THAP8 TNNT1 TRAF3IP3 TRAPPC4 TSHZ3 TSPYL4 TUFT1 TXLNA VPS37C ZC2HC1C ZFYVE26 ZGPAT ZMAT2 ZNF417 ZSCAN12	5 interactors: KDM1A NUP62 RINT1 TFIP11 USHBP1
Entrez ID		24144	79635
HPRD ID		11628	07834
Ensembl ID		ENSG00000100109	ENSG00000176714
Uniprot IDs		Q9UBB9	Q6ZUS5
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Mitotic Cell Cycle Cellular Component Assembly Mitotic Cell Cycle Process Cell Cycle Process Cellular Macromolecular Complex Assembly G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Cell Division Mitotic Nuclear Division Nucleosome Organization Chromatin Assembly Or Disassembly Mitotic Cell Cycle Phase Transition Cytoskeleton Organization Cell Cycle Phase Transition Centrosome Organization Microtubule Anchoring Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Organizing Center Organization Chromosome Organization Gene Expression Nucleosome Assembly Microtubule-based Process Maintenance Of Protein Location In Cell Organelle Assembly Maintenance Of Protein Location Chromatin Assembly Maintenance Of Location In Cell Transcription, DNA-templated ATP-dependent Chromatin Remodeling RNA Metabolic Process Anatomical Structure Development Cellular Localization RNA Biosynthetic Process Positive Regulation Of Protein Oligomerization Protein-DNA Complex Assembly Chromatin Organization Ribonucleoprotein Complex Assembly Cellular Macromolecule Biosynthetic Process Recombinational Repair Nucleobase-containing Compound Metabolic Process Protein Targeting To Golgi Chromatin Remodeling Establishment Of Protein Localization To Golgi Retrograde Transport, Vesicle Recycling Within Golgi Macromolecule Biosynthetic Process DNA Packaging CENP-A Containing Nucleosome Assembly Kidney Smooth Muscle Cell Differentiation	Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Spliceosomal Complex Disassembly Regulation Of Primitive Erythrocyte Differentiation Regulation Of Response To DNA Damage Stimulus Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Regulation Of Intracellular Signal Transduction Positive Regulation Of Megakaryocyte Differentiation Negative Regulation Of Intracellular Signal Transduction Regulation Of DNA Damage Checkpoint Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of ER To Golgi Vesicle-mediated Transport Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Erythrocyte Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Histone H3-K4 Methylation Positive Regulation Of ERBB Signaling Pathway Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Hormone Biosynthetic Process Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hematopoietic Progenitor Cell Differentiation Regulation Of Hormone Metabolic Process Histone Lysine Demethylation Regulation Of Signal Transduction Histone Demethylation Mitotic Nuclear Envelope Disassembly Regulation Of Erythrocyte Differentiation Protein Demethylation Regulation Of Cell Cycle Checkpoint Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Nuclear Envelope Disassembly Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of DNA Binding Negative Regulation Of Protein Metabolic Process Regulation Of Signaling Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death RNA Metabolic Process Negative Regulation Of Ras Protein Signal Transduction
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