RBFOX2 and PTBP1

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		RBFOX2	PTBP1
Gene Name		RNA binding protein, fox-1 homolog (C. elegans) 2	polypyrimidine tract binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleoplasm Nucleolus Membrane Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Transcription Factor Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Definitive Erythrocyte Differentiation RNA Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Intracellular Estrogen Receptor Signaling Pathway Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Dendrite Morphogenesis Neuromuscular Process Controlling Balance	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		50 interactors: APH1A ATN1 ATXN1 ATXN1L BOLL BRD7 C1orf94 CAMK2B CHAF1A DAB1 DAZAP2 DDX5 DEDD2 DMRTB1 ELAVL1 ELAVL2 ESR1 ESR2 GLIS2 GTF2A1L HNRNPAB HNRNPF HNRNPH2 HNRNPK KHDRBS1 MAGED1 MAPK1IP1L MED7 NAF1 NR2E3 POLR3D PSMA3 PSMF1 PTBP1 QKI RBFOX1 RBM22 RBM23 RBM42 RBPMS RERE RHOXF2 RNF8 SF3A1 SMN1 SNRPC TOLLIP U2AF2 VAC14 ZNF137P	27 interactors: APBB1 APP CALCOCO2 CASP3 ELAVL1 FUS HIST3H3 HMGA1 HMGA2 HNRNPAB HNRNPK HNRNPL IL7R NONO PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 ZMYM2
Entrez ID		23543	5725
HPRD ID		15231	02823
Ensembl ID		ENSG00000100320	ENSG00000011304
Uniprot IDs		O43251	P26599
PDB IDs		2CQ3	1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 3ZZY 3ZZZ
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process RNA Processing Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Splicing Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of MRNA Processing Positive Regulation Of Cellular Protein Metabolic Process Metabolic Process DNA-templated Transcription, Initiation	MRNA Metabolic Process MRNA Processing RNA Splicing RNA Processing Gene Expression RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Oncogene-induced Cell Senescence Positive Regulation Of Gene Expression Senescence-associated Heterochromatin Focus Assembly Positive Regulation Of Cellular Senescence Cellular Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Heterochromatin Assembly Cell Morphogenesis DNA Metabolic Process Cell Morphogenesis Involved In Differentiation Anatomical Structure Morphogenesis Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Heterochromatin Organization DNA Catabolic Process, Endonucleolytic Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Cell Cycle Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Stress Regulation Of Cellular Senescence Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway DNA Repair Chromatin Modification Cell Development Regulation Of Stem Cell Maintenance Response To Light Stimulus Positive Regulation Of Cell Death DNA Catabolic Process Cellular Senescence Chromosome Organization Extracellular Matrix Organization
Tagcloud ?		aberrant altering biology discussing editing emerging fmrp focus fus hub huc hud hur neurological nova players polyadenylation processing qki rbp rbps rna rnas roles splicing steps surveillance translational	aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine splicing
Tagcloud (Difference) ?		aberrant altering biology discussing editing emerging fmrp focus fus hub huc hud hur neurological nova players polyadenylation processing qki rbp rbps rna rnas roles steps surveillance translational	aminobutyric ampa amphibians calmodulin camkiialpha clathrin demonstrations elongated exclude fiber gaba immunoblot intriguingly isoxazolepropionic lens lenses morphogenetic neurogenesis nonsense parallels polypyrimidine protrusions psd ptbp2 scaffold spacing spine
Tagcloud (Intersection) ?		splicing