MAPK8IP2 and VPS33B

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		MAPK8IP2	VPS33B
Gene Name		mitogen-activated protein kinase 8 interacting protein 2	vacuolar protein sorting 33 homolog B (yeast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Neuronal Cell Body Protein Complex Neuronal Postsynaptic Density	Cytoplasm Lysosome Lysosomal Membrane Late Endosome HOPS Complex Platelet Alpha Granule Late Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Beta-amyloid Binding MAP-kinase Scaffold Activity Structural Molecule Activity Protein Binding Kinesin Binding Protein Kinase Binding Protein Kinase Activator Activity Protein Complex Binding	Protein Binding
	Biological Process	MAPK Cascade Behavioral Fear Response Signal Complex Assembly JNK Cascade Mating Behavior Regulation Of Receptor Activity Positive Regulation Of Stress-activated MAPK Cascade Social Behavior Positive Regulation Of Protein Kinase Activity Regulation Of JNK Cascade Nonassociative Learning Dendrite Morphogenesis Regulation Of Synaptic Transmission, Glutamatergic Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity	Vesicle Docking Involved In Exocytosis Protein Transport Vesicle-mediated Transport Melanosome Localization Lysosome Localization Membrane Fusion Platelet Alpha Granule Organization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		52 interactors: ADRB2 AFG3L2 APP ASRGL1 BBS10 C14orf1 CFL1 CHN1 CRMP1 DUSP16 EGFR ERBB2 EZH2 FGF12 FSCN1 GBP2 ITSN1 KIFC2 KLC1 LRP1 LRP2 LRP8 MAGED4B MAP2K3 MAP2K7 MAP3K10 MAP3K11 MAP3K12 MAPK10 MAPK8 MAPK8IP1 MAPK8IP3 MAPK9 MASP1 NDUFS6 PLXNA3 PRSS23 RAI1 RBX1 RPS6KB2 SMARCB1 SMS SYNE2 TIAM1 TP53BP2 UNC119 VCP VPS33B VRK2 YY1AP1 ZNF593 ZNF784	6 interactors: APP MAPK8IP2 TNIP1 UVRAG VIPAS39 ZAK
Entrez ID		23542	26276
HPRD ID		09674	10541
Ensembl ID		ENSG00000008735	ENSG00000184056
Uniprot IDs		Q13387	B3KQF6 F5H008 Q9H267
PDB IDs
Enriched GO Terms of Interacting Partners?		Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade JNK Cascade Signal Transduction By Phosphorylation MAPK Cascade Regulation Of Protein Kinase Activity Regulation Of MAPK Cascade Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Kinase Activity JUN Phosphorylation Regulation Of MAP Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of MAP Kinase Activity Response To Stress Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of MAPK Cascade Regulation Of Signal Transduction Response To Light Stimulus Response To External Stimulus Response To Radiation Regulation Of Signaling Intracellular Signal Transduction Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Axon Guidance Regulation Of Intracellular Signal Transduction Signal Transduction Axonogenesis Phosphorylation Cell Part Morphogenesis Axon Development Response To Stimulus Cell Morphogenesis Involved In Neuron Differentiation Response To Abiotic Stimulus Protein Phosphorylation Cellular Response To Stress Signaling	Mating Behavior Mating Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation JNK Cascade Regulation Of Phosphorus Metabolic Process Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Interaction With Host Regulation Of MAPK Cascade Positive Regulation Of Metabolic Process Response To Stress Stress-activated MAPK Cascade Regulation Of Receptor Activity Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Synaptic Growth At Neuromuscular Junction Learning Dendrite Development Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Sexual Reproduction Regulation Of JNK Cascade Collateral Sprouting In Absence Of Injury Regulation Of Stress-activated MAPK Cascade Regulation Of Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Nonassociative Learning MAPK Cascade Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Reproduction Regulation Of Protein Phosphorylation Axon Choice Point Recognition Learning Or Memory Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction By Phosphorylation SNARE Complex Assembly Cognition Neuron Remodeling Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Cellular Protein Complex Assembly Reproductive Process Defense Response Regulation Of Signaling Signal Complex Assembly Cellular Response To Stress Positive Regulation Of Catalytic Activity Cellular Copper Ion Homeostasis
Tagcloud ?			acidification associates atpase attributed coordinating depends dephosphorylation drives endosomal engulfment exclusion fusion luminal lysosome machinery macrophage macrophages maturation mtb multisubunit mycobacterial mycobacterium pathogenicity phagosome ptpa secreted sorting vacuolar
Tagcloud (Difference) ?			acidification associates atpase attributed coordinating depends dephosphorylation drives endosomal engulfment exclusion fusion luminal lysosome machinery macrophage macrophages maturation mtb multisubunit mycobacterial mycobacterium pathogenicity phagosome ptpa secreted sorting vacuolar
Tagcloud (Intersection) ?