AP4E1 and AP4S1

Number of citations of the paper that reports this interaction (PMID 10436028)
54

Data Source:
BioGRID (two hybrid)

		AP4E1	AP4S1
Gene Name		adaptor-related protein complex 4, epsilon 1 subunit	adaptor-related protein complex 4, sigma 1 subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Coated Pit Membrane Coat	Golgi Apparatus Coated Pit
	Molecular Function		Transporter Activity Protein Transporter Activity
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport	Protein Transport
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: AP4B1 AP4S1 ARF1	6 interactors: AFP AP4E1 APP GRB2 GTF2I TEAD3
Entrez ID		23431	11154
HPRD ID		06258	06257
Ensembl ID		ENSG00000081014	ENSG00000100478
Uniprot IDs		B4DM48 Q9UPM8	Q9Y587
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Transport Establishment Of Protein Localization Protein Localization COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Long Term Synaptic Depression Cellular Copper Ion Homeostasis Regulation Of Arp2/3 Complex-mediated Actin Nucleation Dendritic Spine Organization Copper Ion Homeostasis Regulation Of Actin Nucleation Regulation Of Defense Response To Virus By Virus Vesicle Targeting, To, From Or Within Golgi Regulation Of Receptor Internalization Retrograde Vesicle-mediated Transport, Golgi To ER Vesicle Targeting Localization Within Membrane Negative Regulation Of Synaptic Transmission Transport Membrane Budding Regulation Of Defense Response To Virus Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Intracellular Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Phosphatidylinositol Biosynthetic Process	Reproductive Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Transition Between Slow And Fast Fiber Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Transcription Initiation From RNA Polymerase II Promoter Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition DNA-templated Transcription, Initiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Steroid Metabolic Process Positive Regulation Of Stem Cell Maintenance Regulation Of Skeletal Muscle Adaptation Cellular Calcium Ion Homeostasis Negative Regulation Of Cytosolic Calcium Ion Concentration Neuron Remodeling Calcium Ion Homeostasis Branching Involved In Labyrinthine Layer Morphogenesis Signal Transduction Ovulation From Ovarian Follicle Signaling Axon Guidance Vesicle-mediated Transport Cell Communication Cellular Metal Ion Homeostasis Blood Coagulation Cellular Copper Ion Homeostasis Hemostasis Cellular Cation Homeostasis Response To Radiation Cellular Ion Homeostasis Progesterone Metabolic Process Ovulation Metal Ion Homeostasis Labyrinthine Layer Morphogenesis Copper Ion Homeostasis Suckling Behavior
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