MTUS2 and CXCL11

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MTUS2	CXCL11
Gene Name		microtubule associated tumor suppressor candidate 2	chemokine (C-X-C motif) ligand 11
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Cytoplasmic Microtubule	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Microtubule Binding Protein Homodimerization Activity	Protein Binding Chemokine Activity Heparin Binding CXCR3 Chemokine Receptor Binding
	Biological Process		Positive Regulation Of Leukocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Signal Transduction G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Positive Regulation Of CAMP Metabolic Process Response To Lipopolysaccharide Regulation Of Cell Proliferation Positive Regulation Of CAMP-mediated Signaling Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Chemokine-mediated Signaling Pathway
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Insomnia (caffeine-induced) ( 22754043) Obesity-related traits ( 23251661)
Protein-Protein Interactions		167 interactors: AEN AES AFF4 ALS2CR11 AQP1 ARNT2 BMP7 BYSL C14orf105 C19orf66 C1orf109 C1orf216 C20orf195 C21orf58 C8orf34 CATIP CATSPER1 CBX8 CCDC116 CCDC146 CCDC17 CCDC60 CCHCR1 CDC20B CDC73 CDK18 CDK5R1 CDKL3 CEP57L1 CEP95 CERK COG2 CREB5 CRY2 CTSZ CWF19L2 CXCL11 CXCL16 DCDC2B DCTN4 DLGAP5 DMRT3 DOCK2 DTNB FAM13C FAM161A FAM71E2 FAM74A4 FAM90A1 FBXL18 FBXO34 FCHSD2 GAL3ST2 GOLGA2P11 GTF2I GTPBP10 HAUS1 HCK HDAC4 HSF2 IQCE ITGB5 ITSN1 KAT5 KIF1A LENG1 LIMS2 LINC00636 LMO2 LNX1 LOC153684 LRR1 LYSMD1 MAGEA8 MARK4 MFAP1 MTMR6 NDEL1 NDOR1 NELFE NUBPL NUDT10 ODF1 PDE4DIP PIN1 PKP2 PLK4 PLSCR4 POLDIP2 POLDIP3 PPHLN1 PPP1R18 PRKAA1 PRPF31 PSMA1 PTPMT1 RAB3IL1 RGS2 RHPN1 RIBC2 ROBO3 RPA1 RPL9 RTP5 SCEL SDCBP SELM SETD5 SH2D4A SH3RF2 SLC23A1 SLC25A6 SLIRP SMARCE1 SNAI1 SNHG11 SNRPA SNRPB2 SNW1 SPATA8 SPG7 STK16 SYT6 TAF13 THAP7 TP53RK TRIM42 TSGA10IP TSHZ3 TXN2 USP2 WAC WDYHV1 ZBTB38 ZC2HC1C ZFC3H1 ZFP2 ZFP64 ZFYVE21 ZMAT2 ZNF136 ZNF20 ZNF224 ZNF232 ZNF250 ZNF3 ZNF329 ZNF337 ZNF410 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF490 ZNF572 ZNF581 ZNF587 ZNF599 ZNF607 ZNF624 ZNF655 ZNF670 ZNF785 ZNF844 ZSCAN12 ZSCAN26	4 interactors: CCR3 CXCR3 DPP4 MTUS2
Entrez ID		23281	6373
HPRD ID		11108	05329
Ensembl ID			ENSG00000169248
Uniprot IDs		J3KQA9 Q5JR59	O14625
PDB IDs			1RJT
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Mitochondrion Morphogenesis Histone Ubiquitination T Cell Chemotaxis Histone H2B Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Tight Junction Assembly Cellular Response To Lipid Axon Cargo Transport Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Positive Regulation Of Gene Expression Transepithelial Transport Signal Transduction By P53 Class Mediator Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Lymphocyte Chemotaxis Regulation Of Cell Cycle Process Negative Regulation Of Phosphatase Activity T Cell Migration	Chemokine-mediated Signaling Pathway Regulation Of Endothelial Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of Angiogenesis Cell Adhesion Positive Regulation Of Cytosolic Calcium Ion Concentration Locomotion Cytosolic Calcium Ion Homeostasis Chemokine (C-C Motif) Ligand 11 Production Regulation Of Cell Proliferation Regulation Of Angiogenesis Regulation Of Epithelial Cell Proliferation Cellular Calcium Ion Homeostasis Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Extracellular Matrix Disassembly Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Inflammatory Response Negative Regulation Of Execution Phase Of Apoptosis Cellular Cation Homeostasis Cytokine-mediated Signaling Pathway Cellular Ion Homeostasis Regulation Of Cell-cell Adhesion Mediated By Integrin T Cell Chemotaxis Metal Ion Homeostasis Chemokine Production Cellular Chemical Homeostasis Positive Regulation Of Execution Phase Of Apoptosis Ion Homeostasis Positive Regulation Of CAMP-mediated Signaling Cellular Response To Cytokine Stimulus Chemotaxis Lymphocyte Chemotaxis T Cell Migration Cellular Homeostasis Response To Cytokine Regulation Of CAMP-mediated Signaling Regulation Of Execution Phase Of Apoptosis Response To Stress Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cell Migration Lymphocyte Migration Regulation Of Extracellular Matrix Disassembly Chemical Homeostasis Negative Regulation Of Endothelial Cell Proliferation Cell Motility Positive Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Extracellular Matrix Organization Regulation Of Cell Adhesion Mediated By Integrin Cellular Defense Response
Tagcloud ?			academic assessing auc bacilli centre chemoattractant cxcl9 cxcr3 diagnosing differentiating gamma grades ifn immunoassays inducible ligands mig monokine pulmonary radiographic smear sputum surrogate tac tb tertiary usefulness
Tagcloud (Difference) ?			academic assessing auc bacilli centre chemoattractant cxcl9 cxcr3 diagnosing differentiating gamma grades ifn immunoassays inducible ligands mig monokine pulmonary radiographic smear sputum surrogate tac tb tertiary usefulness
Tagcloud (Intersection) ?