SEPT6 and SEPT5

Number of citations of the paper that reports this interaction (PMID 18330356)
4

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		SEPT6	SEPT5
Gene Name		septin 6	septin 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Kinetochore Spindle Synaptic Vesicle Midbody Cleavage Furrow Axon Terminus	Cytoskeleton Plasma Membrane Cell Cortex Synaptic Vesicle Terminal Bouton
	Molecular Function	Protein Binding GTP Binding	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding
	Biological Process	Cytokinesis Viral Process	Cytokinesis Metabolic Process Synaptic Vesicle Targeting Regulation Of Exocytosis Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS			DNA methylation (parent-of-origin) ( 23725790)
Protein-Protein Interactions		13 interactors: CDC42EP2 CDC42EP3 KDM1A MORN4 PLEKHF2 S100A4 SEPT1 SEPT2 SEPT3 SEPT5 SEPT9 TK1 WHSC1L1	18 interactors: APP KAT7 LSM8 MAGEA2B MAPK6 MYOG PARK2 PFN2 SEPT1 SEPT10 SEPT11 SEPT2 SEPT4 SEPT6 SEPT7 SEPT8 STX1A STX4
Entrez ID		23157	5413
HPRD ID		06716	04100
Ensembl ID		ENSG00000125354	ENSG00000184702
Uniprot IDs		F5H1J5 Q14141 Q541S4 Q548C9	G3XAH0 Q99719
PDB IDs		2QAG
Enriched GO Terms of Interacting Partners?		Cell Division Positive Regulation Of Pseudopodium Assembly Cell Cycle Fetal Process Involved In Parturition Regulation Of Primitive Erythrocyte Differentiation Skeletal Muscle Cell Proliferation Positive Regulation Of Actin Filament Polymerization Regulation Of Cell Projection Assembly Positive Regulation Of Protein Polymerization Regulation Of L-glutamate Transport Response To Cortisol Thymidine Metabolic Process Regulation Of Cell Shape Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Synaptic Vesicle Targeting Deoxyribonucleoside Monophosphate Biosynthetic Process Histone H3-K4 Demethylation Histone H3-K27 Methylation Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage	Cell Cycle Cell Division Regulation Of Synaptic Vesicle Transport Regulation Of Neurotransmitter Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Synaptic Transmission Positive Regulation Of Protein Ubiquitination Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Neurotransmitter Transport Regulation Of Synaptic Vesicle Exocytosis Regulation Of Insulin Secretion Regulation Of Protein Ubiquitination Regulation Of Peptide Hormone Secretion Vesicle Fusion Synaptic Vesicle Exocytosis Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Muscle Atrophy Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Hormone Secretion Positive Regulation Of Exocytosis Organelle Organization Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Secretion Organelle Fusion Sperm Mitochondrion Organization Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Synaptic Growth At Neuromuscular Junction Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Protein Linear Polyubiquitination Regulation Of Embryonic Cell Shape Positive Regulation Of Protein Metabolic Process Vesicle Docking Cellular Component Assembly Exocytosis Regulation Of Cellular Component Organization Membrane Docking Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Dopamine Uptake Involved In Synaptic Transmission Collateral Sprouting In Absence Of Injury Regulation Of Protein Localization Regulation Of Protein Secretion Cytokinesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of L-glutamate Transport Neurotransmitter Secretion
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