HABP4 and PIAS3

Number of citations of the paper that reports this interaction (PMID 16455055)
3

Data Source:
HPRD (two hybrid)

		HABP4	PIAS3
Gene Name		hyaluronan binding protein 4	protein inhibitor of activated STAT, 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol Sarcomere	Nucleus Cytoplasm Dendrite Synapse
	Molecular Function	Protein Binding	Protein Binding Protein C-terminus Binding Zinc Ion Binding Potassium Channel Regulator Activity Ligase Activity SUMO Transferase Activity Enzyme Binding Protein N-terminus Binding
	Biological Process	Platelet Degranulation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Blood Coagulation Platelet Activation Negative Regulation Of DNA Binding Cellular Response To Mechanical Stimulus	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Response To Hormone Positive Regulation Of Gene Expression Protein Sumoylation Positive Regulation Of Protein Sumoylation Positive Regulation Of Membrane Potential
Pathways		Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: C1QBP CHD3 DAXX ENO2 FRA10AC1 GNB2L1 HMGXB4 KAT5 PIAS3 PPP1R15A PRKCA PRKCB PRKCD PRKCG PRKCQ PRKCZ PRMT1 SRSF9 SYNCRIP TOPORS TP53 UBE2I VIM YBX1	49 interactors: AR ATF7IP C19orf60 CARHSP1 CBS CREM EP300 ESR1 ESR2 GEMIN4 GFI1 GLUL HABP4 HDAC1 HMGA2 MITF NCOA2 NR3C2 OPN1LW PGR PPP1CA PRPF40A PSMC1 RAC1 RELA SATB1 SERBP1 SERPINA10 SIAH1 SIAH2 SKIL SMAD2 SMAD3 SMAD4 SREBF2 STAT3 SUMO1 SUMO2 SUMO3 TBP TRIM27 TRIM32 TRIM55 TRIM63 UBA1 UBE2I ZFHX3 ZMIZ1 ZMIZ2
Entrez ID		22927	10401
HPRD ID		13628	09068
Ensembl ID		ENSG00000130956	ENSG00000131788
Uniprot IDs		Q5JVS0	B3KNI3 Q6IAR4 Q9Y6X2
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Negative Regulation Of Insulin Receptor Signaling Pathway Apoptotic Process Programmed Cell Death Negative Regulation Of Cellular Metabolic Process Cell Death Death Regulation Of Protein Metabolic Process Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Blood Coagulation Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Hemostasis Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction Platelet Activation Viral Process Regulation Of Body Fluid Levels Negative Regulation Of Signaling Wound Healing Peptidyl-amino Acid Modification Regulation Of RNA Metabolic Process Response To Wounding Chromatin Organization Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Platelet Aggregation Positive Regulation Of Phospholipase Activity Regulation Of Cell Death Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Phospholipase Activity Histone H3-T6 Phosphorylation Positive Regulation Of Lipase Activity Chromatin Modification Enzyme Linked Receptor Protein Signaling Pathway Organelle Organization Positive Regulation Of Signal Transduction Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Amino Acid Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Cell Death Protein Sumoylation	Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Gene Expression Transcription Initiation From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Response To Organic Substance Regulation Of Cellular Process Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Cellular Response To Organic Substance Biosynthetic Process Epithelium Development Regulation Of Signal Transduction Regulation Of Cell Death Regulation Of Signaling Response To Stimulus Cellular Response To Stimulus
Tagcloud ?		9q altered cgi contexts experimentally explain familiar functionally give haplotype hek293t identity inducer insights ki knockdown link microchip overexpression paralogs prompting qrt serbp1 shared similarity sirna thapsigargin transcriptome tumorigenic	achieved atm atr consistently crucial dbc1 deficient diverse establish etoposide finely genotoxic interaction knockdown metabolism modification modifier promoted promotion remarkably senp1 sirt1 sumo sumo1 sumo2 sumoylation switching transactivation ubiquitin
Tagcloud (Difference) ?		9q altered cgi contexts experimentally explain familiar functionally give haplotype hek293t identity inducer insights ki link microchip overexpression paralogs prompting qrt serbp1 shared similarity sirna thapsigargin transcriptome tumorigenic	achieved atm atr consistently crucial dbc1 deficient diverse establish etoposide finely genotoxic interaction metabolism modification modifier promoted promotion remarkably senp1 sirt1 sumo sumo1 sumo2 sumoylation switching transactivation ubiquitin
Tagcloud (Intersection) ?		knockdown