FKBP4 and S100A6

Number of citations of the paper that reports this interaction (PMID 20188096)
7

Data Source:
BioGRID (pull down, affinity chromatography technology)

		FKBP4	S100A6
Gene Name		FK506 binding protein 4, 59kDa	S100 calcium binding protein A6
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Microtubule Neuronal Cell Body Axonal Growth Cone Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Ruffle Nucleus Nuclear Envelope Cytoplasm Cytosol Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding ATP Binding GTP Binding FK506 Binding Protein Binding, Bridging Heat Shock Protein Binding Copper-dependent Protein Binding Glucocorticoid Receptor Binding Poly(A) RNA Binding Tau Protein Binding Phosphoprotein Binding	Calcium Ion Binding Protein Binding Tropomyosin Binding Zinc Ion Binding Ion Transmembrane Transporter Activity Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Folding Steroid Hormone Receptor Complex Assembly Copper Ion Transport Embryo Implantation Negative Regulation Of Neuron Projection Development Androgen Receptor Signaling Pathway Prostate Gland Development Negative Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Protein Complex Localization Cellular Response To Heat Male Sex Differentiation Chaperone-mediated Protein Folding Regulation Of Cellular Response To Heat	Signal Transduction Axonogenesis Ion Transmembrane Transport Positive Regulation Of Fibroblast Proliferation
Pathways		HSF1-dependent transactivation Attenuation phase Cellular response to heat stress
Drugs
Diseases
GWAS		Quantitative traits ( 19197348)
Protein-Protein Interactions		25 interactors: ACVR1 ATOX1 CALM1 CSNK2A1 EGFR ESR1 FES FKBP1A GLMN HSF1 HSP90AA1 HSPA4 IRF4 NR3C1 NR3C2 PHYH PTPN2 S100A1 S100A2 S100A6 SH3BP4 SMURF2 SNCA SQSTM1 STIP1	11 interactors: ANXA11 ANXA2 CACYBP FKBP4 GAPDH MDM2 PEX5 PPID S100B SUGT1 TP53
Entrez ID		2288	6277
HPRD ID		11794	00237
Ensembl ID			ENSG00000197956
Uniprot IDs		Q02790	P06703
PDB IDs		1N1A 1P5Q 1Q1C 1QZ2 4DRJ 4LAV 4LAW 4LAX	1K8U 1K96 1K9K 1K9P
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Cellular Response To Organic Substance Regulation Of Oxidoreductase Activity Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Response To Stimulus Regulation Of Nitric-oxide Synthase Activity Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Stimulus Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Signal Transduction Regulation Of Signal Transduction Response To Lipid Cellular Response To Growth Factor Stimulus Negative Regulation Of Signaling Response To Organic Cyclic Compound Response To Growth Factor Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phospholipase Activity Developmental Process System Development Positive Regulation Of Protein Metabolic Process Cellular Response To Organic Cyclic Compound Signaling Regulation Of Signaling Regulation Of Immune System Process Cell Communication Defense Response Protein Import Into Mitochondrial Outer Membrane Response To Steroid Hormone Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Oxidoreductase Activity Response To Stress Regulation Of Cell Proliferation Positive Regulation Of Nitric Oxide Biosynthetic Process Multicellular Organismal Development Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Innate Immune Response Cellular Response To Glucocorticoid Stimulus Response To Glucocorticoid Anatomical Structure Development Cellular Response To Corticosteroid Stimulus Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Regulation Of Immune Response Response To Corticosteroid	Cellular Response To UV Protein Complex Assembly Cellular Response To Light Stimulus Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Tetramerization Cellular Response To Oxygen Levels Response To UV Cellular Response To Radiation Response To Abiotic Stimulus Regulation Of Protein Oligomerization Cellular Component Assembly Protein Localization Immune Response Immune System Process Regulation Of Signal Transduction By P53 Class Mediator Mitotic Cell Cycle Process Positive Regulation Of Transport Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Mitochondrial Membrane Organization Establishment Of Protein Localization Response To Hypoxia Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Neuron Apoptotic Process Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Response To Antibiotic Innate Immune Response Regulation Of Cell Death Chaperone-mediated Protein Folding Response To Metal Ion Neuron Death Regulation Of Protein Complex Assembly Response To Light Stimulus Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Steroid Hormone Receptor Complex Assembly Peptidyl-cysteine S-trans-nitrosylation Cellular Response To UV-C Cellular Response To Vitamin B1 Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Peptidyl-amino Acid Modification Protein Peptidyl-prolyl Isomerization Regulation Of Fibroblast Proliferation Apoptotic Process Protein Targeting Signal Transduction In Response To DNA Damage
Tagcloud ?			125i annexin ascites ca2 calcyclin cellulose chromatography chymotrypsin database dehydrogenase depended digested eat ehrlich evidenced extracts gel glyceraldehyde homogeneity ions labelled overlay p30 phenyl purified search sepharose similarity spleen
Tagcloud (Difference) ?			125i annexin ascites ca2 calcyclin cellulose chromatography chymotrypsin database dehydrogenase depended digested eat ehrlich evidenced extracts gel glyceraldehyde homogeneity ions labelled overlay p30 phenyl purified search sepharose similarity spleen
Tagcloud (Intersection) ?