ESRRA and DPF2

Number of citations of the paper that reports this interaction (PMID 20400511)
4

Data Source:
BioGRID (pull down)

		ESRRA	DPF2
Gene Name		estrogen-related receptor alpha	D4, zinc and double PHD fingers family 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Microtubule Cytoskeleton Intercellular Bridge	Nuclear Chromatin Nucleoplasm Cytoplasm Centrosome Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Steroid Binding Protein Binding Zinc Ion Binding Protein Domain Specific Binding Sequence-specific DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Organelle Organization Mitochondrion Organization Gene Expression Intracellular Receptor Signaling Pathway Regulation Of Cell Proliferation Steroid Hormone Mediated Signaling Pathway Regulation Of Osteoblast Differentiation Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cartilage Development	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Apoptotic Process Apoptotic Signaling Pathway
Pathways		PPARA activates gene expression Organelle biogenesis and maintenance Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Nuclear Receptor transcription pathway Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS		Crohn's disease ( 21102463)
Protein-Protein Interactions		34 interactors: ADH5 ATXN1 DPF1 DPF2 DPF3 DUT EIF3I ESR1 ESRRG EXOSC6 FUS GTF2B HDAC8 KAT2B LYST MACF1 MAP2K5 NCOA1 NCOA3 NR0B1 NR0B2 NRIP1 NSD1 NXF1 PIAS4 PNRC2 PPARGC1A PRKCD PROX1 SIRT1 SMARCD3 SP1 SRC TNNI2	14 interactors: ESRRA ESRRB ESRRG FHL2 HIST1H3A HIST3H3 LDOC1 LNX1 NFKB2 REL RELB SMARCB1 UPF2 ZNF212
Entrez ID		2101	5977
HPRD ID		07210	03394
Ensembl ID		ENSG00000173153	ENSG00000133884
Uniprot IDs		P11474 Q569H8	B4DT58 J3KMZ8 Q92785
PDB IDs		1XB7 2PJL 3D24 3K6P	3IUF
Enriched GO Terms of Interacting Partners?		Gene Expression Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Receptor Signaling Pathway Biosynthetic Process Nitrogen Compound Metabolic Process DNA-templated Transcription, Initiation Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Regulation Of Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Hormone Stimulus Chromatin Modification Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Androgen Receptor Signaling Pathway Reproductive Structure Development Negative Regulation Of Cellular Metabolic Process Reproductive System Development Chromatin Organization Response To Hormone	Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process NIK/NF-kappaB Signaling Intracellular Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Hormone-mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Metabolic Process Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Metabolic Process Response To Organic Substance DNA-templated Transcription, Initiation Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Follicular Dendritic Cell Differentiation Trophectodermal Cell Proliferation Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Blastocyst Development
Tagcloud ?		biogenesis constituent coregulated ctf1 dap3 elk1 elk4 exploring gabpa gtp hdap3 homoeostasis hox11 microarray mitochondrial nrf oncocytic pparg presenting publicly ribosome runx1 rxra silico tal1 ternary tumourigenesis tumours upregulated	1alpha acetylated androgen associating baf45d biogenesis coactivator coactivators converted derepressed enhances err erralpha fingers hdac1 hela myoblast peroxisome pgc phd proliferator purification recognizing repressive repressor stably steroid superfamily transactivation
Tagcloud (Difference) ?		constituent coregulated ctf1 dap3 elk1 elk4 exploring gabpa gtp hdap3 homoeostasis hox11 microarray mitochondrial nrf oncocytic pparg presenting publicly ribosome runx1 rxra silico tal1 ternary tumourigenesis tumours upregulated	1alpha acetylated androgen associating baf45d coactivator coactivators converted derepressed enhances err erralpha fingers hdac1 hela myoblast peroxisome pgc phd proliferator purification recognizing repressive repressor stably steroid superfamily transactivation
Tagcloud (Intersection) ?		biogenesis