FBL and DDX17

Number of citations of the paper that reports this interaction (PMID 10837141)
15

Data Source:
HPRD (in vivo, two hybrid)

		FBL	DDX17
Gene Name		fibrillarin	DEAD (Asp-Glu-Ala-Asp) box helicase 17
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Granular Component Nucleus Nucleolus Cajal Body Membrane Box C/D SnoRNP Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Membrane
	Molecular Function	RNA Binding Protein Binding Poly(A) RNA Binding Histone-glutamine Methyltransferase Activity	Transcription Coactivator Activity RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity Estrogen Receptor Binding Poly(A) RNA Binding
	Biological Process	Osteoblast Differentiation RRNA Processing TRNA Processing SnoRNA Metabolic Process Histone Glutamine Methylation	Transcription, DNA-templated RNA Processing Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Skeletal Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: DDX17 DDX5 ERG KLF6 MAP3K14 NOP56 PIH1D1 PIN4 PRMT1 PRMT3 PRMT6 PSMB6 RUVBL1 RUVBL2 SMN1 SMN2 SNRPN TAF9 TBC1D17	28 interactors: APBB1 APP BYSL CREBBP CSNK2A1 DDX5 ESR2 FBL GRB2 HDAC1 HNRNPH3 HNRNPK LNX1 NCOA1 NCOA2 NCOA3 PIN1 RBM15 RBM4 SF1 SF3B4 SNRNP70 SORBS3 SRA1 SREK1 U2AF2 WBP11 YWHAG
Entrez ID		2091	10521
HPRD ID		00617	10532
Ensembl ID		ENSG00000105202	ENSG00000100201
Uniprot IDs		P22087	Q59F66 Q92841
PDB IDs		2IPX
Enriched GO Terms of Interacting Partners?		Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine RNA Metabolic Process Peptidyl-arginine N-methylation Peptidyl-amino Acid Modification Histone Arginine Methylation Peptidyl-arginine Methylation Histone Modification Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Chromatin Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Chromatin Organization Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone H4-R3 Methylation Cellular Protein Modification Process Histone H2A Acetylation RNA Processing Chromosome Organization Regulation Of Skeletal Muscle Cell Differentiation Histone Acetylation Histone Methylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation RNA Splicing Protein Acetylation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Protein Methylation Ribonucleoprotein Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Metabolic Process NcRNA Metabolic Process Spliceosomal SnRNP Assembly Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Histone H4 Acetylation	RNA Metabolic Process MRNA Processing RNA Splicing MRNA Metabolic Process RNA Processing Gene Expression Nucleobase-containing Compound Metabolic Process Rhythmic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of MRNA Processing Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of RNA Splicing Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Regulation Of Receptor Activity Histone Modification Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Protein Acetylation Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Cell Differentiation Regulation Of Androgen Receptor Signaling Pathway Labyrinthine Layer Morphogenesis Developmental Process Cellular Response To Hormone Stimulus Regulation Of Signal Transduction Chromatin Modification Embryonic Placenta Morphogenesis Transcription From RNA Polymerase II Promoter
Tagcloud ?		actinomycin character condensed contribution delays differentiation es example fibrillarin hyperdynamic interestingly knockdown latter lif lineages methyltransferase nucleolar nucleoli partial pluripotency pluripotent processing prolonged promoted proper ribosomal rrna stem unique	34a 3a adding auf1 contexts cpeb4 dimension doxorubicin focusing hnrnpd indirect keeps master mcf7 modulated nutlin polysomal preferentially searched srsf1 subpolysomal tardbp transcriptome translational translatome uncoupled uncoupling variations ybx1
Tagcloud (Difference) ?		actinomycin character condensed contribution delays differentiation es example fibrillarin hyperdynamic interestingly knockdown latter lif lineages methyltransferase nucleolar nucleoli partial pluripotency pluripotent processing prolonged promoted proper ribosomal rrna stem unique	34a 3a adding auf1 contexts cpeb4 dimension doxorubicin focusing hnrnpd indirect keeps master mcf7 modulated nutlin polysomal preferentially searched srsf1 subpolysomal tardbp transcriptome translational translatome uncoupled uncoupling variations ybx1
Tagcloud (Intersection) ?