ZBTB7C and SREBF1

Number of citations of the paper that reports this interaction (PMID 22331133)
1

Data Source:
BioGRID (two hybrid)

		ZBTB7C	SREBF1
Gene Name		zinc finger and BTB domain containing 7C	sterol regulatory element binding transcription factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Golgi Membrane Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Protein Complex
	Molecular Function	Nucleic Acid Binding Metal Ion Binding	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Kinase Binding Protein Complex Binding Sterol Response Element Binding Sequence-specific DNA Binding Protein Dimerization Activity
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Heart Rate By Chemical Signal Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Lipid Metabolic Process Aging Circadian Rhythm Cholesterol Metabolic Process Insulin Receptor Signaling Pathway Lipid Biosynthetic Process Cellular Response To Starvation Response To Glucose Positive Regulation Of Triglyceride Biosynthetic Process Regulation Of Fatty Acid Metabolic Process Lung Development Positive Regulation Of Histone Deacetylation Response To Food Response To Retinoic Acid Response To Progesterone Response To Glucagon Response To Drug Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Insulin Secretion Response To CAMP Cellular Response To Fatty Acid
Pathways			RORA activates circadian gene expression
Drugs
Diseases
GWAS			Parkinson's disease ( 21738487)
Protein-Protein Interactions		1 interactors: SREBF1	35 interactors: AR ATXN1 ATXN1L CDK8 CREBBP ESR1 ESR2 GSK3B HNF4A ID3 KLF13 LMNA MAPK1 MAPK3 MED1 MED12 MED13 MED14 MED17 MED23 MED24 MED25 MED26 MED6 MED7 NR0B1 SIRT1 SMARCD3 SP1 SREBF2 SUMO1 TWIST2 UBE2I YY1 ZBTB7C
Entrez ID		201501	6720
HPRD ID		18950	01701
Ensembl ID		ENSG00000184828	ENSG00000072310
Uniprot IDs		A1YPR0 B2RG49	B4DEU6 P36956
PDB IDs			1AM9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Cholesterol Metabolic Process Regulation Of Heart Rate By Chemical Signal Positive Regulation Of Triglyceride Biosynthetic Process Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Histone Deacetylation Regulation Of Cholesterol Biosynthetic Process Response To Food Positive Regulation Of Protein Deacetylation Positive Regulation Of Steroid Metabolic Process Regulation Of Cholesterol Metabolic Process Regulation Of Triglyceride Metabolic Process Regulation Of Histone Deacetylation Negative Regulation Of Insulin Secretion Negative Regulation Of Peptide Secretion Cellular Response To Fatty Acid Regulation Of Protein Deacetylation Response To Progesterone Response To Glucagon Positive Regulation Of Lipid Biosynthetic Process Negative Regulation Of Hormone Secretion Response To Fatty Acid Regulation Of Steroid Biosynthetic Process Positive Regulation Of Histone Modification Regulation Of Heart Rate Regulation Of Fatty Acid Metabolic Process Regulation Of Steroid Metabolic Process Negative Regulation Of Protein Secretion Cholesterol Metabolic Process Response To CAMP Response To Retinoic Acid Regulation Of Histone Modification Sterol Metabolic Process Response To Glucose Regulation Of Lipid Biosynthetic Process Cellular Response To Starvation Insulin Receptor Signaling Pathway Response To Organophosphorus Negative Regulation Of Secretion By Cell Regulation Of Heart Contraction Circadian Rhythm Cellular Response To Acid Chemical Response To Purine-containing Compound Negative Regulation Of Secretion Cellular Response To Nutrient Levels Response To Starvation Negative Regulation Of Protein Transport Response To Carbohydrate Regulation Of Insulin Secretion Regulation Of Chromosome Organization	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Transcription From RNA Polymerase II Promoter Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Positive Regulation Of Gene Expression Gene Expression Positive Regulation Of Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Androgen Receptor Signaling Pathway Cellular Metabolic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Regulation Of Cellular Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Cellular Response To Heat Regulation Of Cell Differentiation Organ Development Cell Differentiation Metabolic Process
Tagcloud ?		acting bcor cdkn1a corepressors deacetylation defect disrupting embryonic enhancement finger gaps genetically interacted kr kruppel mef mefs ncor oligomerization p21waf1 physically pok poz relies repress repressor suppress transactivation zinc	aberrations acly biphasic cascade chemoprevention citrate desaturase disturbed fads2 fatty harboring hbv hcc hepatocytes lipid livers lyase metabolism mtor pre remarkably s2 starting sterol subsided synchronized transgenic tumorigenesis upregulate
Tagcloud (Difference) ?		acting bcor cdkn1a corepressors deacetylation defect disrupting embryonic enhancement finger gaps genetically interacted kr kruppel mef mefs ncor oligomerization p21waf1 physically pok poz relies repress repressor suppress transactivation zinc	aberrations acly biphasic cascade chemoprevention citrate desaturase disturbed fads2 fatty harboring hbv hcc hepatocytes lipid livers lyase metabolism mtor pre remarkably s2 starting sterol subsided synchronized transgenic tumorigenesis upregulate
Tagcloud (Intersection) ?