EEF1A1 and KIF1B

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1A1	KIF1B
Gene Name		eukaryotic translation elongation factor 1 alpha 1	kinesin family member 1B
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Extracellular Vesicular Exosome	Mitochondrion Kinesin Complex Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection
	Molecular Function	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Poly(A) RNA Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Translational Elongation Gene Expression Cellular Protein Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Anterograde Axon Cargo Transport Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport Mitochondrion Transport Along Microtubule
Pathways		HSF1 activation Translation Cellular response to heat stress Peptide chain elongation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS			Hepatocellular carcinoma ( 20676096) Mean platelet volume ( 22139419) Multiple sclerosis ( 18997785)
Protein-Protein Interactions		123 interactors: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCDC130 CCL18 CDC25A CDKN1A CKS2 COX17 CRADD CRCT1 CSRP2 DARS DIABLO DLEU1 DUSP7 DYNLL1 EIF3F EXOSC4 FAS GADD45A GADD45G GSK3B HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B KRAS LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP RAB27A RAP2A RBBP8 RFC5 RGS12 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB9 SFN SHBG SMAD2 SMAD4 SMN1 SNCA SPP1 SSR1 STAT6 STMN2 SULT1E1 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSPY1 TSPYL2 TTR UBQLN4 WARS XPO5 XRN2 YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1	16 interactors: ARHGAP1 BRCA1 CALM1 CHP1 CPEB1 DLG1 DLG2 DLG3 DLG4 EEF1A1 GIPC1 INADL SIAH1 SNTA1 STARD13 YWHAG
Entrez ID		1915	23095
HPRD ID		00559	05818
Ensembl ID		ENSG00000156508	ENSG00000054523
Uniprot IDs		P68104 Q6IPS9	O60333
PDB IDs		1SYW	2EH0
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cell Death Death Regulation Of Phosphorylation Developmental Process Regulation Of Phosphorus Metabolic Process Response To Stimulus Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Cell Differentiation Anatomical Structure Development Regulation Of Catalytic Activity Regulation Of Signal Transduction Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Regulation Of Cell Death Multicellular Organismal Development Regulation Of Apoptotic Process Cellular Response To Stimulus Response To Stress Cellular Response To Growth Factor Stimulus Response To External Stimulus Positive Regulation Of Protein Modification Process Regulation Of Signaling Cellular Response To Stress Positive Regulation Of Programmed Cell Death Response To Growth Factor Positive Regulation Of Catalytic Activity System Development Positive Regulation Of Phosphorylation Positive Regulation Of Cell Death Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Nervous System Development Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transferase Activity Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Kinase Activity	Receptor Localization To Synapse Protein Localization To Synapse Receptor Clustering Nucleotide Phosphorylation Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Signaling Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphatase Activity Membrane Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Negative Regulation Of Protein Metabolic Process Response To Stimulus Synaptic Transmission Regulation Of Dephosphorylation Regulation Of Sodium Ion Transmembrane Transport Regulation Of Signal Transduction Regulation Of Synaptic Plasticity Regulation Of Catalytic Activity Regulation Of Ion Transmembrane Transport Negative Regulation Of Phosphatase Activity Regulation Of Sodium Ion Transport Negative Regulation Of Dephosphorylation Cellular Response To Stimulus Cellular Protein Localization Regulation Of Cellular Protein Metabolic Process Cell-cell Signaling Regulation Of Cellular Process Signaling Cell Communication Regulation Of Protein Metabolic Process Regulation Of Ion Transport Regulation Of Synaptic Transmission Cellular Localization Signal Transduction Protein Localization To Membrane Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Protein Stability Intracellular Signal Transduction Regulation Of Ion Transmembrane Transporter Activity Axon Guidance Regulation Of Transmembrane Transporter Activity Protein Localization Cortical Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Protein Autophosphorylation Posttranscriptional Regulation Of Gene Expression Establishment Or Maintenance Of Cell Polarity Regulation Of Phosphorus Metabolic Process Regulation Of Cell Cycle Process
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668	clues depdc5 directions dp dq exome g1896a gwass hbv hepatocarcinogenesis hla hotspots htert integrations landscape mica mutational pnpla3 pose possibilities rtm204i rtm204v shall technologies threats throughput transitions underlined warrant
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668	clues depdc5 directions dp dq exome g1896a gwass hbv hepatocarcinogenesis hla hotspots htert integrations landscape mica mutational pnpla3 pose possibilities rtm204i rtm204v shall technologies threats throughput transitions underlined warrant
Tagcloud (Intersection) ?