NR0B1 and NRIP1

Number of citations of the paper that reports this interaction (PMID 11459805)
7

Data Source:
BioGRID (two hybrid, pull down)
HPRD (in vitro, two hybrid, in vivo)

		NR0B1	NRIP1
Gene Name		nuclear receptor subfamily 0, group B, member 1	nuclear receptor interacting protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Polysomal Ribosome	Histone Deacetylase Complex Nucleus Nucleoplasm Nucleolus Nuclear Speck Cell Junction
	Molecular Function	DNA Binding Steroid Hormone Receptor Activity Transcription Corepressor Activity RNA Binding Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding DNA Hairpin Binding Steroid Hormone Receptor Binding Protein Homodimerization Activity Sequence-specific DNA Binding AF-2 Domain Binding	Core Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Estrogen Receptor Binding Nuclear Hormone Receptor Binding Glucocorticoid Receptor Binding Histone Deacetylase Binding Retinoid X Receptor Binding Androgen Receptor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Steroid Biosynthetic Process Spermatogenesis Protein Localization Gonad Development Male Gonad Development Gene Expression Hypothalamus Development Pituitary Gland Development Male Sex Determination Adrenal Gland Development Intracellular Receptor Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Leydig Cell Differentiation Response To Immobilization Stress Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated Sertoli Cell Differentiation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Ovarian Follicle Rupture Transcription, DNA-templated Circadian Rhythm Lipid Storage Androgen Receptor Signaling Pathway Circadian Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs		Tretinoin Dexamethasone
Diseases
GWAS			Breast cancer ( 23535729) Cognitive performance ( 19734545)
Protein-Protein Interactions		16 interactors: AR COPS2 ESR1 ESR2 ESRRA ESRRG NR3C1 NR5A1 NRIP1 PGR POU5F1 PPARG RNF31 RORA SNW1 SREBF1	53 interactors: ACTN2 AHR APP AR ARPC3 BRCA1 CCDC85B CDK8 CEP70 CIB1 CTBP1 CTBP2 DNMT1 DNMT3A DNMT3B E2F1 ESR1 ESR2 ESRRA ESRRB ESRRG HDAC1 HDAC2 HDAC3 HDAC5 HDAC9 HNF4A JUN KAT2B LDOC1 MAP3K7 NR0B1 NR1H2 NR1H3 NR2C1 NR3C1 NR5A1 NR5A2 PPARA PPARD PPARG PRMT1 RARA RORB RXRA RXRB TEX11 THRA THRB TNFRSF14 TRAF2 VDR YWHAH
Entrez ID		190	8204
HPRD ID		08362	03927
Ensembl ID			ENSG00000180530
Uniprot IDs		F1D8P4 P51843	A8K171 P48552
PDB IDs			2GPO 2GPP
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Lipid Cellular Response To Steroid Hormone Stimulus Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Response To Steroid Hormone Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Hormone Stimulus Response To Lipid Cellular Response To Organic Cyclic Compound Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Response To Organic Cyclic Compound Response To Hormone RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Signal Transduction Cellular Response To Organic Substance Signaling Positive Regulation Of Cellular Metabolic Process Cell Communication Nucleobase-containing Compound Metabolic Process Rhythmic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Organ Development Cellular Nitrogen Compound Metabolic Process Cellular Response To Stimulus System Development Response To Organic Substance Ovulation Cycle Process Nitrogen Compound Metabolic Process	Steroid Hormone Mediated Signaling Pathway Intracellular Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Steroid Hormone Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Positive Regulation Of Gene Expression Cellular Response To Hormone Stimulus Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Response To Organic Substance Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Steroid Hormone Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Response To Organic Cyclic Compound Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Response To Hormone Gene Expression Response To Lipid Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Signal Transduction
Tagcloud ?		always cd99 chondrosarcoma comprising differentiate diffuse e2f3 es ewing ewsr1 exceptional extraskeletal fli1 gold immunohistochemical marker merkel mesenchymal myxoid neoplasm neuroblastomas nkx2 olfactory powerful reinforces round sarcoma singly srcts	accurately blastx classifications close cog degs density differentially downloaded enriched esr1 genecodis gotm gse7429 hundred includes language mapped mineral module modules obtain omnibus osteoprotegerin packages ppid searched software vdr
Tagcloud (Difference) ?		always cd99 chondrosarcoma comprising differentiate diffuse e2f3 es ewing ewsr1 exceptional extraskeletal fli1 gold immunohistochemical marker merkel mesenchymal myxoid neoplasm neuroblastomas nkx2 olfactory powerful reinforces round sarcoma singly srcts	accurately blastx classifications close cog degs density differentially downloaded enriched esr1 genecodis gotm gse7429 hundred includes language mapped mineral module modules obtain omnibus osteoprotegerin packages ppid searched software vdr
Tagcloud (Intersection) ?