DYX1C1 and SPDL1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		DYX1C1	SPDL1
Gene Name		dyslexia susceptibility 1 candidate 1	spindle apparatus coiled-coil protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Spindle Pole Condensed Chromosome Outer Kinetochore Nucleus Microtubule Organizing Center Cytosol
	Molecular Function	Protein Binding Estrogen Receptor Binding	Protein Binding Enzyme Binding Kinetochore Binding
	Biological Process	Neuron Migration Cilium Movement Determination Of Left/right Symmetry Regulation Of Intracellular Estrogen Receptor Signaling Pathway Outer Dynein Arm Assembly Inner Dynein Arm Assembly Regulation Of Proteasomal Protein Catabolic Process	Establishment Of Mitotic Spindle Orientation Mitotic Cell Cycle Mitotic Metaphase Plate Congression Spindle Checkpoint Protein Localization To Kinetochore Cell Division
Pathways			Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: HSPA1A KDM1A SPDL1 STUB1	9 interactors: CA8 DYX1C1 GPS2 ITSN1 KIAA1377 PPP1R18 RTP5 TRAF4 USP15
Entrez ID		161582	54908
HPRD ID		10568	08623
Ensembl ID		ENSG00000256061	ENSG00000040275
Uniprot IDs		Q8WXU2	Q96EA4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Erythrocyte Differentiation Regulation Of Hormone Metabolic Process Regulation Of Erythrocyte Differentiation Negative Regulation Of Protein Binding Positive Regulation Of Myeloid Cell Differentiation Negative Regulation Of Binding Regulation Of Primitive Erythrocyte Differentiation Response To Unfolded Protein Regulation Of Protein Binding Positive Regulation Of Chaperone-mediated Protein Complex Assembly Cellular Heat Acclimation Regulation Of Myeloid Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Protein Ubiquitination Negative Regulation Of Signaling Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Binding Ubiquitin-dependent SMAD Protein Catabolic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Protein Localization To Kinetochore Positive Regulation Of Megakaryocyte Differentiation Negative Regulation Of Inclusion Body Assembly Protein Localization To Chromosome, Centromeric Region Positive Regulation Of Hormone Biosynthetic Process Regulation Of Glucocorticoid Metabolic Process Regulation Of Cellular Component Organization Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cellular Protein Metabolic Process Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Misfolded Protein Granulocyte Differentiation Regulation Of Protein Metabolic Process Regulation Of Inclusion Body Assembly Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Protein Refolding Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Hormone Biosynthetic Process Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Mitotic Metaphase Plate Congression Protein Localization To Chromosome	Regulation Of Signal Transduction Histone H2B Conserved C-terminal Lysine Deubiquitination Regulation Of Signaling Regulation Of JNK Cascade Intracellular Signal Transduction Regulation Of Stress-activated MAPK Cascade Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Inner Dynein Arm Assembly Regulation Of Protein Metabolic Process Outer Dynein Arm Assembly Monoubiquitinated Protein Deubiquitination Positive Regulation Of Protein Homodimerization Activity
Tagcloud ?		11p15 15q21 18p11 1p34 2p 3p12 6p21 6q13 c2orf3 dcdc2 disabled dyx2 dyx3 dyx4 dyx5 dyx6 dyx7 dyx8 dyx9 ekn1 kiaa0319 mrpl19 neurobiologic q12 q16 rd robo1 xq27
Tagcloud (Difference) ?		11p15 15q21 18p11 1p34 2p 3p12 6p21 6q13 c2orf3 dcdc2 disabled dyx2 dyx3 dyx4 dyx5 dyx6 dyx7 dyx8 dyx9 ekn1 kiaa0319 mrpl19 neurobiologic q12 q16 rd robo1 xq27
Tagcloud (Intersection) ?