ZNF483 and TRIM69

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZNF483	TRIM69
Gene Name		zinc finger protein 483	tripartite motif containing 69
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Plasma Membrane Nuclear Speck
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Apoptotic Process Protein Ubiquitination
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Menarche (age at onset) ( 21102462 23599027) Pubertal anthropometrics ( 23449627)
Protein-Protein Interactions		8 interactors: APP KIAA0368 MEOX2 TRIM69 USHBP1 ZNF24 ZNF496 ZSCAN22	22 interactors: APP ASNS ATP5G1 DVL1 FAM110A FKBP1B HAUS1 IYD KRT17 LARP1B MAGEA4 NEK8 PML PPP1R18 RECK RSPH14 SF1 SF3A3 SKIL SYNE4 TRIM44 ZNF483
Entrez ID		158399	140691
HPRD ID		18345	11518
Ensembl ID		ENSG00000173258	ENSG00000185880
Uniprot IDs		A7MD06 Q8TF39	Q86WT6
PDB IDs		2CTU
Enriched GO Terms of Interacting Partners?		Neuron Death Synaptic Growth At Neuromuscular Junction RNA Metabolic Process Collateral Sprouting In Absence Of Injury Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Somite Specification Axon Choice Point Recognition Transcription, DNA-templated Cell Death Death Neuron Remodeling Cellular Metabolic Process RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Segment Specification Regulation Of Gene Expression Cellular Copper Ion Homeostasis Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Nitrogen Compound Metabolic Process Mating Behavior	MRNA 3'-splice Site Recognition Collateral Sprouting Maintenance Of Protein Location In Nucleus Anatomical Structure Development System Development Negative Regulation Of Catalytic Activity Protein Localization To Nucleus Regulation Of Cell Development Developmental Process Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Cell Development Morphogenesis Of An Epithelium MRNA Splice Site Selection Multicellular Organismal Development Organ Development Positive Regulation Of Neuron Projection Development Regulation Of Neuron Differentiation Neuromuscular Junction Development Cellular Nitrogen Compound Metabolic Process Epithelium Development Negative Regulation Of Translation In Response To Oxidative Stress L-asparagine Biosynthetic Process Regulation Of Hormone Levels Anatomical Structure Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Tissue Development Regulation Of Translation Spliceosomal Complex Assembly Positive Regulation Of Cell Projection Organization Tissue Morphogenesis Positive Regulation Of Cell Cycle Regulation Of Proteolysis Cellular Calcium Ion Homeostasis Positive Regulation Of Proteolysis Cell Differentiation Calcium Ion Homeostasis Regulation Of Neurogenesis Positive Regulation Of Protein Metabolic Process Gene Expression Cellular Component Assembly Regulation Of Calcium Ion Transport Into Cytosol Synaptic Growth At Neuromuscular Junction Positive Regulation Of Sequestering Of Calcium Ion Positive Regulation Of Neuron Differentiation Nitrogen Compound Metabolic Process Response To Light Stimulus Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process
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