ARL6IP6 and ARL6

Number of citations of the paper that reports this interaction (PMID 10508919)
7

Data Source:
HPRD (two hybrid)

		ARL6IP6	ARL6
Gene Name		ADP-ribosylation factor-like 6 interacting protein 6	ADP-ribosylation factor-like 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm Cytosol Axonemal Microtubule Plasma Membrane Cilium Axoneme Membrane Membrane Coat BBSome Ciliary Membrane Extracellular Vesicular Exosome Primary Cilium
	Molecular Function		Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding
	Biological Process		Protein Targeting To Membrane Organelle Organization Small GTPase Mediated Signal Transduction Determination Of Left/right Symmetry Brain Development Visual Perception Regulation Of Smoothened Signaling Pathway Retina Layer Formation Wnt Signaling Pathway Melanosome Transport Cilium Assembly Fat Cell Differentiation Intermembrane Transport Protein Polymerization Protein Localization To Cilium
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS			Male infertility ( 19478329)
Protein-Protein Interactions		2 interactors: APP ARL6	6 interactors: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B
Entrez ID		151188	84100
HPRD ID		12485	10588
Ensembl ID		ENSG00000177917	ENSG00000113966
Uniprot IDs		B3KMZ5 Q8N6S5	Q9H0F7
PDB IDs			2H57
Enriched GO Terms of Interacting Partners?		Intermembrane Transport Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Brain Development Protein Localization To Cilium Head Development Cell Projection Morphogenesis Cell Part Morphogenesis Cellular Copper Ion Homeostasis Central Nervous System Development Copper Ion Homeostasis Suckling Behavior Cell Morphogenesis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Retina Layer Formation Cell Projection Organization Neurological System Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Melanosome Transport Endoplasmic Reticulum Calcium Ion Homeostasis Pigment Granule Transport RNA Polyadenylation Neuron Recognition Establishment Of Melanosome Localization Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Melanosome Localization Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Intracellular Transport Axon Cargo Transport Mating Neuromuscular Junction Development Neural Retina Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Retina Morphogenesis In Camera-type Eye Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Cellular Pigmentation Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway	Cotranslational Protein Targeting To Membrane Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Negative Regulation Of Mitochondrial Membrane Potential Retrograde Protein Transport, ER To Cytosol
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