PTP4A3 and FNTB

Number of citations of the paper that reports this interaction (PMID 10747914)
24

Data Source:
HPRD (in vitro)

		PTP4A3	FNTB
Gene Name		protein tyrosine phosphatase type IVA, member 3	farnesyltransferase, CAAX box, beta
Image
Gene Ontology Annotations	Cellular Component	Early Endosome Plasma Membrane	Cytosol Microtubule Associated Complex Protein Farnesyltransferase Complex
	Molecular Function	Prenylated Protein Tyrosine Phosphatase Activity	Farnesyltranstransferase Activity Protein Farnesyltransferase Activity Protein Binding Drug Binding Zinc Ion Binding Isoprenoid Binding Peptide Binding
	Biological Process	Peptidyl-tyrosine Dephosphorylation Endothelial Cell Migration	Phototransduction, Visible Light Negative Regulation Of Cell Proliferation Response To Inorganic Substance Response To Organic Cyclic Compound Rhodopsin Mediated Signaling Pathway Protein Farnesylation Regulation Of Rhodopsin Mediated Signaling Pathway Response To Cytokine Wound Healing Positive Regulation Of Cell Cycle Positive Regulation Of Fibroblast Proliferation Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process
Pathways			Inactivation, recovery and regulation of the phototransduction cascade Visual phototransduction The phototransduction cascade Diseases associated with visual transduction
Drugs
Diseases
GWAS			Blood trace element (Zn levels) ( 23720494) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517)
Protein-Protein Interactions		2 interactors: FNTA FNTB	9 interactors: CENPF FNTA GBP1 HDAC6 HRAS KRAS PTP4A3 RAP2A RRAS2
Entrez ID		11156	2342
HPRD ID		05922	00608
Ensembl ID			ENSG00000257365
Uniprot IDs		O75365	P49356
PDB IDs		1R6H 1V3A	1JCQ 1LD7 1LD8 1MZC 1S63 1SA4 1TN6 2F0Y 2H6F 2H6G 2H6H 2H6I 2IEJ 3E37
Enriched GO Terms of Interacting Partners?		Protein Farnesylation Protein Prenylation Regulation Of Rhodopsin Mediated Signaling Pathway Rhodopsin Mediated Signaling Pathway Phototransduction, Visible Light Detection Of Visible Light Cellular Response To Light Stimulus Phototransduction Detection Of Light Stimulus Cellular Response To Radiation Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Positive Regulation Of Tubulin Deacetylation Response To Light Stimulus Response To Radiation Regulation Of Tubulin Deacetylation Positive Regulation Of Deacetylase Activity Detection Of Stimulus Protein Geranylgeranylation Neurotransmitter Receptor Metabolic Process Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Positive Regulation Of Protein Deacetylation Response To Abiotic Stimulus G-protein Coupled Receptor Signaling Pathway Regulation Of Protein Deacetylation Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Positive Regulation Of Fibroblast Proliferation Response To External Stimulus Execution Phase Of Apoptosis Receptor Metabolic Process Regulation Of Fibroblast Proliferation Regulation Of Receptor Activity Response To Organic Substance Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Signal Transduction Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Signaling Cell Surface Receptor Signaling Pathway Cellular Protein Modification Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Cell Cycle	Ras Protein Signal Transduction Positive Regulation Of Rac Protein Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Cell Migration Response To Growth Factor Small GTPase Mediated Signal Transduction Regulation Of Cell Motility Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Locomotion Regulation Of Synaptic Transmission, GABAergic Regulation Of Cellular Component Movement Regulation Of Rac Protein Signal Transduction Social Behavior Epithelial Tube Branching Involved In Lung Morphogenesis Regulation Of Neuron Death Positive Regulation Of Ras Protein Signal Transduction Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Response To Light Stimulus Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Small GTPase Mediated Signal Transduction Visual Learning Response To External Stimulus Positive Regulation Of Locomotion Visual Behavior Activation Of MAPKK Activity Lung Morphogenesis Cellular Response To Organic Substance Regulation Of Oxidoreductase Activity Positive Regulation Of Tubulin Deacetylation Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Hsp90 Deacetylation Associative Learning Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Response To Radiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Muscle Structure Development Positive Regulation Of Chaperone-mediated Protein Complex Assembly Polyubiquitinated Misfolded Protein Transport Regulation Of Receptor Activity Cell Communication Cellular Response To Growth Factor Stimulus Response To Organic Substance Learning Actin Cytoskeleton Organization
Tagcloud ?		aberrations ann arbor barr bcl2 cd10 cd320 cd45 cd56 clinicopathologic cutaneous dnmt3b ebv epstein extranodal hodgkin ic immunocompetent immunodeficiency immunologic pbl pbls plasmablastic positivity recipients summarized testis unpublished	annotation atad5 automatically becn1 cdkn2a centered clusterone cytoscape david e2f e2f1 geneways kegg kras language module modules mp neurofibromatosis nf1 nf2 nsclc orthologous phenotypes proven successively systemically thyroglobulin visualization
Tagcloud (Difference) ?		aberrations ann arbor barr bcl2 cd10 cd320 cd45 cd56 clinicopathologic cutaneous dnmt3b ebv epstein extranodal hodgkin ic immunocompetent immunodeficiency immunologic pbl pbls plasmablastic positivity recipients summarized testis unpublished	annotation atad5 automatically becn1 cdkn2a centered clusterone cytoscape david e2f e2f1 geneways kegg kras language module modules mp neurofibromatosis nf1 nf2 nsclc orthologous phenotypes proven successively systemically thyroglobulin visualization
Tagcloud (Intersection) ?