NUDT21 and CPSF6

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, biochemical)
HPRD (two hybrid, in vitro)

		NUDT21	CPSF6
Gene Name		nudix (nucleoside diphosphate linked moiety X)-type motif 21	cleavage and polyadenylation specific factor 6, 68kDa
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome MRNA Cleavage Factor Complex Paraspeckles	Nucleus Nucleoplasm MRNA Cleavage Factor Complex Membrane Ribonucleoprotein Complex Paraspeckles
	Molecular Function	RNA Binding MRNA Binding Protein Binding Hydrolase Activity AU-rich Element Binding Protein Homodimerization Activity Histone Deacetylase Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding MRNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Processing RNA Splicing Gene Expression MRNA 3'-end Processing Protein Tetramerization	MRNA Polyadenylation MRNA Processing Protein Tetramerization
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs mRNA 3'-end processing	Signaling by FGFR in disease Signaling by FGFR1 mutants Signaling by FGFR mutants Signaling by FGFR1 fusion mutants
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		51 interactors: A2M ATXN1 CARM1 CLP1 CPSF6 CPSF7 CTNND2 DBN1 DNMT3L DYNC1I1 EED EEF1G EXOSC6 F13A1 FBN3 FLAD1 FUNDC2 GOLGA2 HSF4 IKZF1 ITCH JMJD1C KIAA1377 KIFAP3 MASP1 MYL6 NEDD4 NGEF NIF3L1 POLR2C PSMF1 PTN PYCR1 RBM48 RCC1 RNF19A RPLP1 SEMA5B SF3B1 SHC1 SHFM1 SLC44A1 SNCAIP SNRNP70 SRPK1 TCERG1 TLE1 TRA2A TRIM27 WWOX ZBTB48	23 interactors: APBB1 ARMC7 CSNK2A1 EWSR1 GIN1 ITCH ITSN2 KLHL12 NCK2 NEDD4 NUDT21 OTUB2 PLSCR1 PPIL1 PRPF40A SRSF7 TCERG1 TOLLIP UBAC1 UBQLN4 WBP4 WWP1 WWP2
Entrez ID		11051	11052
HPRD ID		05400	05401
Ensembl ID		ENSG00000167005	ENSG00000111605
Uniprot IDs		O43809	B4DSU9 Q16630
PDB IDs		2CL3 2J8Q 3BAP 3BHO 3MDG 3MDI 3N9U 3P5T 3P6Y 3Q2S 3Q2T	3P5T 3P6Y 3Q2S 3Q2T 4B4N
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Process Cellular Metabolic Process Viral Process Protein K63-linked Ubiquitination RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Protein Polyubiquitination Negative Regulation Of Complement Activation MRNA 3'-end Processing Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Immune System Process Developmental Process RNA 3'-end Processing Cellular Macromolecule Biosynthetic Process Regulation Of Dendrite Development Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression By Genetic Imprinting Blood Coagulation Macromolecule Biosynthetic Process Hemostasis Protein Oligomerization MRNA Polyadenylation Anatomical Structure Development	Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Interaction With Host Protein K63-linked Ubiquitination Viral Entry Into Host Cell Entry Into Host Cell Locomotion Protein Ubiquitination RNA Splicing Protein Modification By Small Protein Conjugation Cellular Metabolic Process MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing RNA Metabolic Process Cellular Protein Modification Process Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Gene Expression Protein Polyubiquitination Regulation Of Potassium Ion Transmembrane Transport Termination Of RNA Polymerase II Transcription Viral Life Cycle Protein Monoubiquitination Regulation Of RNA Metabolic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of Thymidylate Synthase Biosynthetic Process Transmission Of Virus Development Involved In Symbiotic Interaction Nucleobase-containing Compound Metabolic Process Positive Regulation Of Protein Catabolic Process Modification-dependent Protein Catabolic Process Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Potassium Ion Transport Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Catabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Regulation Of Nitrogen Compound Metabolic Process DNA-templated Transcription, Termination Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process MRNA 3'-end Processing Regulation Of Protein Metabolic Process
Tagcloud ?			abilities assembled believe bi bi2 ca cai capsid complexes core crowding cyclophilin cyclosporine destabilize destabilized destabilizes extracts fate hiv ixn macromolecular nc pf74 powerful productive solely stability stabilize stabilized
Tagcloud (Difference) ?			abilities assembled believe bi bi2 ca cai capsid complexes core crowding cyclophilin cyclosporine destabilize destabilized destabilizes extracts fate hiv ixn macromolecular nc pf74 powerful productive solely stability stabilize stabilized
Tagcloud (Intersection) ?