Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
DBF4 and ORC3
Number of citations of the paper that reports this interaction (PMID
12441400
)
37
Data Source:
HPRD
(two hybrid, in vivo)
DBF4
ORC3
Gene Name
DBF4 zinc finger
origin recognition complex, subunit 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Origin Recognition Complex
Nucleoplasm
Nuclear Origin Of Replication Recognition Complex
Molecular Function
Nucleic Acid Binding
Enzyme Activator Activity
Zinc Ion Binding
DNA Replication Origin Binding
Protein Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
Positive Regulation Of Catalytic Activity
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
DNA Replication
Neural Precursor Cell Proliferation
Pathways
G1/S Transition
G2/M Checkpoints
Activation of ATR in response to replication stress
Activation of the pre-replicative complex
DNA Replication Pre-Initiation
M/G1 Transition
Cell Cycle Checkpoints
Activation of the pre-replicative complex
Mitotic G1-G1/S phases
Cell Cycle, Mitotic
G2/M Checkpoints
Activation of the pre-replicative complex
Activation of the pre-replicative complex
Orc1 removal from chromatin
Assembly of the pre-replicative complex
Activation of ATR in response to replication stress
G1/S Transition
Assembly of the ORC complex at the origin of replication
Removal of licensing factors from origins
Mitotic G1-G1/S phases
Switching of origins to a post-replicative state
E2F mediated regulation of DNA replication
Synthesis of DNA
DNA Replication Pre-Initiation
Regulation of DNA replication
M/G1 Transition
S Phase
CDC6 association with the ORC:origin complex
Cell Cycle, Mitotic
Orc1 removal from chromatin
E2F-enabled inhibition of pre-replication complex formation
Cell Cycle Checkpoints
Association of licensing factors with the pre-replicative complex
CDT1 association with the CDC6:ORC:origin complex
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
17 interactors:
BRCA1
CDC7
CDK2
CHAF1A
CHEK2
LSM8
MCM2
MCM3
MCM4
MCM6
MCM7
MEN1
ORC1
ORC2
ORC3
ORC5
ORC6
18 interactors:
APP
CCNE2
CDC45
CDC6
CDK4
DBF4
HIST3H3
HIST4H4
MCM10
MCM4
MCM5
MCM7
ORC1
ORC2
ORC4
ORC5
ORC6
TERF2
Entrez ID
10926
23595
HPRD ID
10371
05398
Ensembl ID
ENSG00000006634
ENSG00000135336
Uniprot IDs
B7Z8C6
Q9UBU7
Q9UBD5
PDB IDs
4F99
4F9A
4F9B
4F9C
Enriched GO Terms of Interacting Partners
?
DNA Replication
DNA Replication Initiation
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
DNA Metabolic Process
DNA-dependent DNA Replication
Cell Cycle
Cell Cycle Process
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Heterocycle Metabolic Process
Macromolecule Biosynthetic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Nitrogen Compound Metabolic Process
DNA Unwinding Involved In DNA Replication
Biosynthetic Process
DNA Duplex Unwinding
DNA Geometric Change
DNA Conformation Change
Cellular Response To DNA Damage Stimulus
Chromosome Organization
Cellular Metabolic Process
Regulation Of DNA Replication
DNA Repair
Cellular Response To Stress
Organelle Organization
Regulation Of Nuclear Cell Cycle DNA Replication
Signal Transduction In Response To DNA Damage
Positive Regulation Of DNA-dependent DNA Replication
Metabolic Process
Response To Ionizing Radiation
Positive Regulation Of DNA Metabolic Process
Double-strand Break Repair
Cellular Response To Epidermal Growth Factor Stimulus
DNA Damage Checkpoint
Response To Epidermal Growth Factor
Negative Regulation Of Cell Cycle
Positive Regulation Of Histone Methylation
Regulation Of Cell Cycle Process
Regulation Of Cell Cycle
Positive Regulation Of Cell Cycle Process
Negative Regulation Of DNA Replication
Cell Cycle Checkpoint
Regulation Of Cell Cycle Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
DNA Replication
DNA Replication Initiation
Mitotic Cell Cycle
DNA Metabolic Process
DNA-dependent DNA Replication
Mitotic Cell Cycle Process
Cell Cycle
Cell Cycle Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
DNA Strand Elongation Involved In DNA Replication
Cellular Macromolecule Biosynthetic Process
DNA Strand Elongation
Macromolecule Biosynthetic Process
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Cellular Metabolic Process
DNA Duplex Unwinding
Biosynthetic Process
DNA Geometric Change
Chromosome Organization
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
DNA Conformation Change
Positive Regulation Of Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Cycle Process
Regulation Of Cell Cycle Phase Transition
Telomere Maintenance
DNA Replication Checkpoint
DNA Unwinding Involved In DNA Replication
Regulation Of Cell Cycle
Positive Regulation Of Cell Cycle
Metabolic Process
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Positive Regulation Of Cell Cycle G1/S Phase Transition
Organelle Organization
Regulation Of Mitotic Cell Cycle
Cell Division
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Negative Regulation Of DNA Replication
Cell Cycle Checkpoint
Tagcloud
?
bud
cdc28
cdc4
cdc7
cln1
cln2
cln3
commited
conceivable
cyclins
dsc1
duplication
else
firstly
hartley
hfs1
jackson
mcb
p34cdc28
pole
principally
redundancy
rosamond
sbf
scb
scm4
smith
swi6
unpublished
Tagcloud (Difference)
?
bud
cdc28
cdc4
cdc7
cln1
cln2
cln3
commited
conceivable
cyclins
dsc1
duplication
else
firstly
hartley
hfs1
jackson
mcb
p34cdc28
pole
principally
redundancy
rosamond
sbf
scb
scm4
smith
swi6
unpublished
Tagcloud (Intersection)
?