SPAG5 and AMOTL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SPAG5	AMOTL2
Gene Name		sperm associated antigen 5	angiomotin like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Midbody Microtubule Plus-end Mitotic Spindle	Cytosol Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Spindle Organization Chromosome Segregation Cell Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore	Wnt Signaling Pathway Hippo Signaling
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: AMOTL2 ARNT2 ATN1 BARD1 C1orf109 CCDC33 CCHCR1 CDC20B CDK1 CHCHD3 DCX EIF4E2 EIF4ENIF1 FBXO28 FMR1 GOLGA8EP GOLGA8F HAUS1 IQCE KANSL1 LGALS14 LINGO1 ODF1 ORC6 POLR2L RBM41 SH2D4A SMARCE1 SNAP47 SNAPIN TSHZ3 TTC23 ZC2HC1C ZFC3H1 ZMAT2	52 interactors: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MYO5B NDC80 NFIL3 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPP1 THRA TMCC2 TRAF2 TRIM27 WDYHV1 ZBED1 ZGPAT
Entrez ID		10615	51421
HPRD ID		10246	16485
Ensembl ID		ENSG00000076382	ENSG00000114019
Uniprot IDs		Q96R06	Q9Y2J4
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Fusion Negative Regulation Of Gene Expression Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Fusion Negative Regulation Of Cellular Metabolic Process Developmental Process Multicellular Organismal Development Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Positive Regulation Of Late Endosome To Lysosome Transport Pronuclear Fusion Nervous System Development Vesicle Fusion Synaptic Vesicle Exocytosis Negative Regulation Of Biosynthetic Process Negative Regulation Of MRNA 3'-end Processing Central Nervous System Development Regulation Of Glial Cell Differentiation Terminal Button Organization Autophagic Vacuole Maturation Negative Regulation Of Translation	Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Protein Localization Histone H2B Ubiquitination Regulation Of Cellular Localization Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination Mitotic Cell Cycle Organelle Organization Chromosome Organization Protein Ubiquitination Histone Monoubiquitination Negative Regulation Of Viral Transcription Cell Cycle Negative Regulation Of Transcription, DNA-templated Protein Modification By Small Protein Conjugation Regulation Of Establishment Of Protein Localization Protein K63-linked Ubiquitination Histone Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Protein Trimerization Negative Regulation Of Determination Of Dorsal Identity Regulation Of Metaphase Plate Congression Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Protein Metabolic Process Response To Organic Substance Cellular Response To Glucagon Stimulus
Tagcloud ?		aligned amenable avenues baz2a bioinformatic candidates cdk13 chem dapk1 digest dilution dst exosc3 hdms hierarchical inhbe kat2b kif20b linkages noninvasive pancreatic proteomics resectable silva smc1b synapt tryptic unsupervised urgent	actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Difference) ?		aligned amenable avenues baz2a bioinformatic candidates cdk13 chem dapk1 digest dilution dst exosc3 hdms hierarchical inhbe kat2b kif20b linkages noninvasive pancreatic proteomics resectable silva smc1b synapt tryptic unsupervised urgent	actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Intersection) ?