HP

Gene Name		haptoglobin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Haptoglobin-hemoglobin Complex Extracellular Vesicular Exosome Endocytic Vesicle Lumen Blood Microparticle
	Molecular Function	Catalytic Activity Protein Binding Antioxidant Activity Hemoglobin Binding
	Biological Process	Immune System Process Receptor-mediated Endocytosis Defense Response Acute-phase Response Metabolic Process Positive Regulation Of Cell Death Response To Hydrogen Peroxide Defense Response To Bacterium Negative Regulation Of Oxidoreductase Activity Negative Regulation Of Hydrogen Peroxide Catabolic Process
Pathways		Scavenging of heme from plasma
Drugs
Diseases
GWAS		Cholesterol, total ( 20686565) Haptoglobin levels ( 22403646) LDL cholesterol ( 20686565) Metabolite levels ( 22916037)
Protein-protein Interactions		20 interactors: ADAMTS4 ATP7B C1RL CD163 CD22 GADD45G GRB2 HBB ITGAM ITGB2 LAMC3 MVP RBBP6 RPL11 SMAD3 TBL1X TGM2 TP63 VKORC1 WASL
Entrez ID		3240
HPRD ID		00772
Ensembl ID		ENSG00000257017
Uniprot IDs		P00738 Q6PEJ8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Body Fluid Levels Response To Stress Wound Healing Multicellular Organismal Development Response To Wounding Blood Coagulation Hemostasis Response To Stimulus Tissue Development Leukocyte Migration Involved In Inflammatory Response Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Immune Response Defense Response Developmental Process Positive Regulation Of Cell Death Anatomical Structure Development Homotypic Cell-cell Adhesion Protein Complex Assembly Positive Regulation Of Immune Response System Development Endocytosis Cellular Extravasation Activated T Cell Proliferation Cell Activation Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Reactive Oxygen Species Metabolic Process Cell Adhesion Organ Development Protein Oligomerization Innate Immune Response Positive Regulation Of Nitric Oxide Biosynthetic Process Cell Surface Receptor Signaling Pathway Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Immune Response Regulation Of Immune System Process Immune Response-regulating Signaling Pathway Positive Regulation Of Cytoskeleton Organization Gland Development Neutrophil Chemotaxis Positive Regulation Of Immune System Process Morphogenesis Of An Epithelium Neutrophil Migration Leukocyte Migration Single Organismal Cell-cell Adhesion Positive Regulation Of Transforming Growth Factor Beta3 Production Epidermal Cell Division Ectoderm And Mesoderm Interaction Granulocyte Chemotaxis Regulation Of Nitric Oxide Biosynthetic Process
Tagcloud ?		antibody cd19 cd3 cd4 cd8 controversial dialysis dr hemodialysis hla hs humoral iii miv multivalent parameters percentages phenomenon restore session strikingly subgroups supplementation supplemented uremia vaccinated vaccination zn znso4