DSCAM

Gene Name		Down syndrome cell adhesion molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Membrane Axon Growth Cone
	Molecular Function	Protein Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Adhesion Nervous System Development Locomotory Behavior Positive Regulation Of Phosphorylation Dendrite Morphogenesis Positive Regulation Of Axon Extension Involved In Axon Guidance Post-embryonic Retina Morphogenesis In Camera-type Eye Dendrite Self-avoidance
Pathways		DSCAM interactions
Drugs
Diseases
GWAS		Neutrophil count ( 21507922) Non-small cell lung cancer ( 21079520) Obesity-related traits ( 23251661)
Protein-protein Interactions		1 interactors: PAK1
Entrez ID		1826
HPRD ID		03953
Ensembl ID		ENSG00000171587
Uniprot IDs		O60469 Q8WY19
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Histone H3-T11 Phosphorylation Contact Inhibition Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Intracellular Estrogen Receptor Signaling Pathway Hyperosmotic Response Activation Of JUN Kinase Activity Histone Phosphorylation Positive Regulation Of Stress Fiber Assembly Peptidyl-threonine Phosphorylation Receptor Clustering Neuromuscular Junction Development Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Stress Fiber Assembly Actin Cytoskeleton Reorganization Positive Regulation Of JUN Kinase Activity T Cell Costimulation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of JUN Kinase Activity JNK Cascade Response To Osmotic Stress Ephrin Receptor Signaling Pathway Epithelial Cell Migration Vascular Endothelial Growth Factor Receptor Signaling Pathway Epithelium Migration Regulation Of Peptidyl-serine Phosphorylation T Cell Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Dendrite Development Antigen Receptor-mediated Signaling Pathway Activation Of MAPK Activity Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of JNK Cascade Synapse Organization Ameboidal-type Cell Migration Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Cytoskeleton Organization Branching Morphogenesis Of An Epithelial Tube Protein Autophosphorylation Cellular Response To Insulin Stimulus Positive Regulation Of T Cell Activation Positive Regulation Of MAP Kinase Activity
Tagcloud ?		agenesis axon axons bulb callosum collapse commissural commissures cone convergent corpus dcc deleted draxin explants forebrain guidance hetero heteros knockouts neogenin netrin neurite neurites olfactory outgrowth repulsion subnanomolar unc5s