PAIP1

Gene Name		poly(A) binding protein interacting protein 1
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding Translation Activator Activity
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Translational Initiation Gene Expression Positive Regulation Of Translation MRNA Stabilization
Pathways		Deadenylation of mRNA Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: EIF4A1 PABPC1 UBR5 WWP2
Entrez ID		10605
HPRD ID		05539
Ensembl ID		ENSG00000172239
Uniprot IDs		Q9H074
PDB IDs		1JH4 3NTW 3RK6
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Catabolic Process Nuclear-transcribed MRNA Poly(A) Tail Shortening Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process MRNA 3'-end Processing RNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Protein Polyubiquitination RNA Catabolic Process Negative Regulation Of Histone H2A K63-linked Ubiquitination Translational Initiation Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Progesterone Receptor Signaling Pathway Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Double-strand Break Repair Cellular Protein Metabolic Process Negative Regulation Of DNA Repair Positive Regulation Of Catenin Import Into Nucleus Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Processing Positive Regulation Of Protein Import Into Nucleus, Translocation Aromatic Compound Catabolic Process Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Modification-dependent Protein Catabolic Process Regulation Of MRNA 3'-end Processing MRNA Metabolic Process Protein Metabolic Process Regulation Of Protein Import Into Nucleus, Translocation Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process RNA Processing Protein Ubiquitination Positive Regulation Of MRNA Catabolic Process Regulation Of Catenin Import Into Nucleus Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Protein Transport MRNA Stabilization Regulation Of Double-strand Break Repair Translation Regulation Of Establishment Of Protein Localization Regulation Of Potassium Ion Transmembrane Transporter Activity
Tagcloud ?		4g abrogated consequent eif3 eif3f eif3g eif4g enhancement eukaryotic initiation interacting interaction mtorc1 pabp phosphorylate phosphorylates poly pp242 rapamycin ribosomal s6 s6k s6k1 shrna simultaneous stimulate stimulates tail translation