PTBP3 and TNFSF15

		PTBP3	TNFSF15
Description		polypyrimidine tract binding protein 3	TNF superfamily member 15
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Binding MRNA Binding	Signaling Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	MRNA Processing RNA Splicing Anatomical Structure Morphogenesis Negative Regulation Of RNA Splicing Erythrocyte Maturation Regulation Of RNA Splicing Regulation Of Cell Differentiation	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Immune Response Signal Transduction Activation Of NF-kappaB-inducing Kinase Activity
Pathways			TNFs bind their physiological receptors
Drugs
Diseases
GWAS		Obstetric antiphospholipid syndrome ( 28424481) Panic disorder ( 31712720)	Asthma ( 32296059) Behcet's disease ( 33393726) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 30500874 21102463 32581322 26891255 23266558) Inflammatory bowel disease ( 27569725 18758464 23128233) Leprosy ( 20018961 25642632) Metabolite levels ( 23823483) Pediatric autoimmune diseases ( 26301688) Primary biliary cholangitis ( 28425483 23000144 28062665 30643196) Ulcerative colitis ( 20848476 21297633) Ulcerative colitis or Crohn's disease ( 21699788)
Interacting Genes		57 interacting genes: APP MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7C TNFSF15	9 interacting genes: DELEC1 FKBP15 OAT PTBP3 SLC46A2 SRSF11 TMEM126A TNFRSF25 TNFRSF6B
Entrez ID		9991	9966
HPRD ID		09603	04956
Ensembl ID		ENSG00000119314	ENSG00000181634
Uniprot IDs		A0A024R163 O95758	A0A0U5JA19 O95150
PDB IDs			2O0O 2QE3 2RE9 2RJK 2RJL 3K51 3MI8
Enriched GO Terms of Interacting Partners?
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