NR1D2 and RGN

Number of citations of the paper that reports this interaction (PubMedID 15604093)
56

Data Source:
HPRD (two hybrid)

		NR1D2	RGN
Description		nuclear receptor subfamily 1 group D member 2	regucalcin
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Nucleus Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific Double-stranded DNA Binding	Gluconolactonase Activity Calcium Ion Binding Zinc Ion Binding Enzyme Regulator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Hormone-mediated Signaling Pathway Regulation Of Lipid Metabolic Process Cell Differentiation Intracellular Receptor Signaling Pathway Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Circadian Behavior Regulation Of Inflammatory Response Negative Regulation Of Inflammatory Response Lipid Homeostasis Energy Homeostasis Regulation Of Skeletal Muscle Cell Differentiation	Kidney Development Negative Regulation Of Protein Kinase Activity Cellular Calcium Ion Homeostasis Spermatogenesis Aging Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Phosphatase Activity L-ascorbic Acid Biosynthetic Process Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of ATPase Activity Negative Regulation Of GTPase Activity Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Negative Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of Epithelial Cell Proliferation Regulation Of Calcium-mediated Signaling Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Liver Regeneration Negative Regulation Of Flagellated Sperm Motility Positive Regulation Of Superoxide Dismutase Activity Positive Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Bone Development Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Calcium-dependent ATPase Activity Negative Regulation Of DNA Catabolic Process Positive Regulation Of DUTP Diphosphatase Activity Negative Regulation Of Leucine-tRNA Ligase Activity Negative Regulation Of DNA Biosynthetic Process
Pathways		Nuclear Receptor transcription pathway
Drugs		SR-9009 SR-9011	Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Acne (severe) ( 24927181) Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Asthma ( 29273806) Cognitive ability ( 29186694) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Metabolite levels ( 23823483) Parkinson's disease progression (cognitive) ( 33111402) Refractive error ( 32231278)
Interacting Genes		53 interacting genes: CRY1 CSNK1E CSNK2A2 CUL1 CYSRT1 DELEC1 EFEMP2 GTF2B HDAC1 HOXA1 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP3-2 KRTAP3-3 KRTAP4-2 KRTAP5-6 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LGALS8 MEOX2 MID2 MYLIP MYO15B NBPF19 NCOA5 NCOR1 NOTCH2NLA NR1D1 PCSK5 PRMT6 PROP1 RBPMS RGN RORC SIN3B TAF6 TAF9 TBC1D21 TENT5B TRIM27 TRIM55 TRIM63 TRIP6 UBE2I ZNF587	2 interacting genes: NR1D2 THRA
Entrez ID		9975	9104
HPRD ID		03809	02196
Ensembl ID		ENSG00000174738	ENSG00000130988
Uniprot IDs		B4DXD3 F1D8P2 Q14995	Q15493 V9HWF8
PDB IDs		2V0V 2V7C 3CQV 4N73 6WMQ 6WMS	3G4E 3G4H 4GNB 4GNC
Enriched GO Terms of Interacting Partners?
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