CCS and APBA1

Number of citations of the paper that reports this interaction (PubMedID 11115513)
7

Data Source:
HPRD (in vivo, in vitro)

		CCS	APBA1
Description		copper chaperone for superoxide dismutase	amyloid beta precursor protein binding family A member 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Dendritic Spine Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse
	Molecular Function	Superoxide Dismutase Activity Copper Ion Binding Protein Binding Protein-disulfide Reductase Activity Cadherin Binding	Amyloid-beta Binding Protein Binding
	Biological Process	Superoxide Metabolic Process Protein Maturation By Copper Ion Transfer Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Positive Regulation Of Oxidoreductase Activity	In Utero Embryonic Development Intracellular Protein Transport Cell Adhesion Chemical Synaptic Transmission Nervous System Development Locomotory Behavior Axo-dendritic Transport Regulation Of Gene Expression Glutamate Secretion Gamma-aminobutyric Acid Secretion Multicellular Organism Growth Protein-containing Complex Assembly Regulation Of Synaptic Vesicle Exocytosis
Pathways		Detoxification of Reactive Oxygen Species Detoxification of Reactive Oxygen Species	Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Bipolar disorder ( 21926972)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Refractive error ( 32231278)
Interacting Genes		3 interacting genes: APBA1 SOD1 YWHAG	17 interacting genes: APP ARF3 ARF4 CACNA1B CASK CCS CNTNAP3 CNTNAP4 HTR2C KCNJ12 KIF17 LIN7B NOTCH1 NRXN1 PSEN1 STX1A STXBP1
Entrez ID		9973	320
HPRD ID		04841	03879
Ensembl ID		ENSG00000173992	ENSG00000107282
Uniprot IDs		O14618	Q02410
PDB IDs		1DO5 2CRL 2RSQ 6FN8 6FOL 6FON 6FP6	1AQC 1U37 1U38 1U39 1U3B 1X11 1X45 1Y7N
Enriched GO Terms of Interacting Partners?
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