MAFB and HOXD12

Number of citations of the paper that reports this interaction (PubMedID 11036080)
12

Data Source:
BioGRID (pull down)

		MAFB	HOXD12
Description		MAF bZIP transcription factor B	homeobox D12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Segment Specification Sensory Organ Development Respiratory Gaseous Exchange By Respiratory System Rhombomere 5 Development Rhombomere 6 Development Abducens Nerve Formation T Cell Differentiation In Thymus Brain Segmentation Inner Ear Morphogenesis Fat Cell Differentiation Regulation Of Myeloid Cell Differentiation Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Osteoclast Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Thymus Development	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Embryonic Digit Morphogenesis
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Adult body size ( 32376654) Apolipoprotein B levels ( 32203549) Aspartate aminotransferase levels ( 33547301) Birth weight ( 31043758 27680694) Bone mineral density (hip) ( 30172743) Cholesterol, total ( 24097068 25961943 20686565) Cleft lip with or without cleft palate ( 28054174) Cognitive decline rate in late mild cognitive impairment ( 26252872) Drug-induced Stevens-Johnson syndrome or toxic epidermal necrolysis (SJS/TEN) ( 21221126) Dupuytren's disease ( 28886342 21732829) Height ( 25282103) Iron status biomarkers (ferritin levels) ( 33536631) LDL cholesterol ( 24097068 19060906 25961943 20686565) LDL cholesterol levels ( 32203549 28334899) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Low density lipoprotein cholesterol levels ( 33339817) Metabolite levels (lipoprotein measures) ( 27005778) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 25775280) Obesity-related traits ( 23251661) Orofacial clefts ( 28054174) Paneth cell defects in Crohn's disease ( 28352666) Plasma parathyroid hormone levels ( 30134803) QT interval (ambient particulate matter interaction) ( 28749367) Red blood cell count ( 32888494) Response to TNF antagonist treatment ( 18615156) Serum alkaline phosphatase levels ( 33547301) Serum total protein level ( 29403010) Spleen volume ( 34128465) Total body bone mineral density ( 29304378) Total cholesterol levels ( 33339817) Triglyceride levels ( 32203549) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Male-pattern baldness ( 28196072)
Interacting Genes		12 interacting genes: ATF4 BACH1 FOS FOSL1 HOXD12 JUN KRTAP4-2 MAF STK4 ZDHHC2 ZFP64 ZWINT	17 interacting genes: ACTN3 CABP2 CREBBP DTX2 FGF14 FRS3 MAF MAFB MAFF MAFG MAFK MEIS1 MKRN3 POLR1C TFAP2D TRAF1 TTC19
Entrez ID		9935	3238
HPRD ID		07129	00871
Ensembl ID		ENSG00000204103	ENSG00000170178
Uniprot IDs		Q9Y5Q3	P35452
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?