ARNT2 and TAX1BP3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		ARNT2	TAX1BP3
Description		aryl hydrocarbon receptor nuclear translocator 2	Tax1 binding protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Aryl Hydrocarbon Receptor Complex	Fibrillar Center Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Aryl Hydrocarbon Receptor Binding Protein-containing Complex Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding Beta-catenin Binding Protein C-terminus Binding
	Biological Process	Response To Hypoxia In Utero Embryonic Development Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Brain Development Positive Regulation Of Cell Population Proliferation Response To Estradiol Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Rho Protein Signal Transduction Negative Regulation Of Cell Population Proliferation Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Activation Of GTPase Activity Negative Regulation Of Protein Localization To Cell Surface
Pathways		PPARA activates gene expression Phase I - Functionalization of compounds Endogenous sterols Xenobiotics Aryl hydrocarbon receptor signalling	RHO GTPases Activate Rhotekin and Rhophilins
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Attention deficit hyperactivity disorder ( 29325848) Bipolar disorder ( 20351715) Body mass index ( 26426971) Gut microbiota relative abundance (unclassified genus belonging to family Erysipelotrichaceae) ( 33208821) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		71 interacting genes: ADAMTSL4 AHR AP1M1 AP3M1 APP ARNT CALCOCO2 CAPN7 CCDC33 CDR2 CEP57L1 CEP63 CTBP1 DGCR6 DTX2 DYDC1 EPAS1 FAAP20 GOLGA2 HIF1A IKZF3 KIFC3 LMO2 LMO4 LZTS2 MAGEA4 MAGED1 MEIS2 MEOX2 MIPOL1 MTDH MTUS2 NCOA3 NDE1 NPAS2 NPAS3 NPAS4 OSGIN1 PDE4DIP PLSCR1 PSMB1 RBCK1 REL RFX6 RIMBP3 RINT1 SH3GL2 SIM1 SIM2 SORBS3 SPAG5 SSBP3 SSX2IP STK16 SYCE1 TACC3 TADA2A TAX1BP3 TFIP11 TRAF1 TRAF2 TRIM23 TRIM27 TRIM37 TRIM42 TRIP6 TSPOAP1 USHBP1 USP7 VPS52 ZNF341	13 interacting genes: ARNT2 CDK5RAP3 CTNNB1 DTX1 GATA1 GLS GLS2 PLK4 RNF183 RTKN STAU1 TCEA2 TRIM29
Entrez ID		9915	30851
HPRD ID		06915	18160
Ensembl ID		ENSG00000172379	ENSG00000213977
Uniprot IDs		Q7Z3A3 Q86TN1 Q9HBZ2 X5DQN9	A0A087X282 O14907
PDB IDs			2KG2 2L4S 2L4T 2VZ5 3GJ9 3SFJ 4E3B 4NNL 4NNM
Enriched GO Terms of Interacting Partners?
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