G3BP2 and CDKL2

		G3BP2	CDKL2
Description		G3BP stress granule assembly factor 2	cyclin dependent kinase like 2
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GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Centrosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding Signaling Receptor Complex Adaptor Activity	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding Protein Serine Kinase Activity
	Biological Process	Cytoplasmic Sequestering Of NF-kappaB Ras Protein Signal Transduction Stress Granule Assembly Innate Immune Response MRNA Transport Protein Homooligomerization Positive Regulation Of Stress Granule Assembly	Protein Phosphorylation Signal Transduction Sex Differentiation Regulation Of Cell Cycle
Pathways
Drugs			Fostamatinib
Diseases
GWAS		HDL cholesterol levels ( 32203549) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763) Testicular germ cell tumor ( 28604728)	Subjective response to lithium treatment in bipolar disorder ( 26503763) Testicular germ cell tumor ( 28604728)
Interacting Genes		66 interacting genes: AGO4 CDKL2 DANCR MDM2 MIR1-1 MIR106A MIR106B MIR107 MIR10B MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR19A MIR19B1 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR363 MIR429 MIR7-1 MIR7-2 MIR7-3 MIR92A1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NFKB1 NFKBIA OGT PHACTR2 PIN1 SDAD1 USO1 ZNF618	3 interacting genes: APP CBL G3BP2
Entrez ID		9908	8999
HPRD ID		06570	16021
Ensembl ID		ENSG00000138757	ENSG00000138769
Uniprot IDs		A0A024RDB2 A0A024RDE5 Q9UN86	A0A140VJG1 B4DH08 J3KNE8 Q92772
PDB IDs		5DRV	4AAA 4BBM
Enriched GO Terms of Interacting Partners?
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