CDC5L and EMID1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		CDC5L	EMID1
Description		cell division cycle 5 like	EMI domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Nuclear Speck Perinuclear Region Of Cytoplasm U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Extracellular Region Collagen Trimer Endoplasmic Reticulum Golgi Apparatus Extracellular Matrix
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding Protein Phosphatase 1 Binding Protein Kinase Binding Leucine Zipper Domain Binding WD40-repeat Domain Binding
	Biological Process	DNA Damage Checkpoint Signaling Mitotic Cell Cycle MRNA Splicing, Via Spliceosome DNA Repair Regulation Of Transcription By RNA Polymerase II Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Interleukin-2 Cellular Response To Wortmannin Cellular Response To Nerve Growth Factor Stimulus Cellular Response To Prolactin
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Chin dimples ( 27182965) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) FEV1 ( 30804560) Height ( 28552196) Ischemic stroke ( 26089329) Lung function (FVC) ( 30804560) Male-pattern baldness ( 27182965) Monobrow ( 27182965) Nose morphology ( 29921221) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis ( 22763110) Osteoarthritis of the hand ( 28855172) Serum alkaline phosphatase levels ( 33547301) Stroke (ischemic) ( 22941190) Trunk fat mass adjusted for trunk lean mass ( 32239398)	Breast cancer ( 23535729) Diverticular disease ( 30177863) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Intraocular pressure ( 29617998 29785010 31959993 30054594) Lymphocyte counts ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Neutrophil count ( 32888494) Pancreatic cancer ( 25086665) Platelet count ( 32888494) Plateletcrit ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Triglyceride levels in HIV infection ( 33109212) White blood cell count ( 32888494)
Interacting Genes		95 interacting genes: AKAP6 AKAP9 BICRAL CALM1 CCDC136 CDC42 CDK2 CDKN1A CDKN2A CDT1 CTNNBL1 DISC1 DIXDC1 DST EMID1 ERG EXOC1 EXOC7 GOLGA2 GOLGA8EP GOLGA8F GRB14 GSE1 HNRNPM HOOK1 KALRN KANK2 KANSL1 KDM1A KIF3C KIF5B KRT18 LDOC1 LMO2 MACF1 MCM10 MCM3 MCM4 MCM5 MELK MIR106B MIR107 MIR143 MIR200B MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR429 MIRLET7A2 MIRLET7D MIRLET7E MIRLET7G MIRLET7I MTUS2 MYT1L OGT ORC1 ORC2 ORC5 PCBD2 PDE4DIP PLRG1 PPFIA2 PPP1CA PPP1R13B PPP1R8 PRPF3 RPA1 RPA2 RPA3 SFR1 SH3BP5 SMARCD1 SPTBN1 SYNE1 SYNPO TP53BP2 TRAF3IP1 TRAK1 TRIO TTF2 TXLNA USHBP1 VPS52 WWC1 YWHAG YWHAQ YWHAZ ZNF35 ZNF451 ZRANB1 ZSCAN1	2 interacting genes: CDC5L COL26A1
Entrez ID		988	129080
HPRD ID		04184	09936
Ensembl ID		ENSG00000096401	ENSG00000186998
Uniprot IDs		Q99459	B0QYK5 Q96A84
PDB IDs		2DIM 2DIN 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P 7AAV 7ABG 7ABH 7ABI
Enriched GO Terms of Interacting Partners?
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