TOMM70 and TBC1D23

		TOMM70	TBC1D23
Description		translocase of outer mitochondrial membrane 70	TBC1 domain family member 23
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane Integral Component Of Membrane Extracellular Exosome	Golgi Apparatus Trans-Golgi Network Cytosol Cytoplasmic Vesicle
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding	Protein Binding
	Biological Process	Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix Positive Regulation Of Interferon-beta Production Regulation Of Apoptotic Process Protein Insertion Into Mitochondrial Inner Membrane Cellular Response To Virus	Brain Development Vesicle-mediated Transport Neuron Projection Development Retrograde Transport, Endosome To Golgi Vesicle Tethering To Golgi Embryonic Brain Development
Pathways		Mitochondrial protein import DDX58/IFIH1-mediated induction of interferon-alpha/beta PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases
Drugs
Diseases
GWAS			Axial length ( 24144296) Refractive error ( 32231278) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		18 interacting genes: CTNNA2 DCBLD2 FOXC1 HSP90AA1 HSPA1A HSPA1B HSPB1 IRF3 KIF2C NIT2 OGT OR5K4 PRKN PSAP SNAPIN TBC1D23 TFG TMEM45A	13 interacting genes: CAGE1 EHD2 EIF3B FAM214B KRTAP10-3 KRTAP10-8 KRTAP10-9 KRTAP4-12 NOPCHAP1 SSBP3 STK11 TOMM70 WDR62
Entrez ID		9868	55773
HPRD ID		16194	07727
Ensembl ID		ENSG00000154174	ENSG00000036054
Uniprot IDs		O94826	Q9NUY8
PDB IDs		7KDT	6JL7 6JM5
Enriched GO Terms of Interacting Partners?
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