MAGI2 and CTNNB1

  • Number of citations of the paper that reports this interaction (PubMedID 11826105)
  • 40
  • Data Source:
  • HPRD (in vivo)

MAGI2

CTNNB1

Description membrane associated guanylate kinase, WW and PDZ domain containing 2 catenin beta 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 23007406)
  • Adult body size ( 32376654)
  • Adverse response to drug ( 30420678)
  • Airway wall thickness ( 25517131)
  • Bitter beverage consumption ( 31046077)
  • Body mass index ( 28892062 25673413)
  • Body size at age 10 ( 32376654)
  • Bronchopulmonary dysplasia ( 23897914)
  • Chronotype ( 30696823)
  • Computer vision syndrome ( 33941792)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • General risk tolerance (MTAG) ( 30643258)
  • Hippocampal atrophy ( 19668339)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • LDL cholesterol levels x short total sleep time interaction (1df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Lead levels in blood ( 25820613)
  • Low density lipoprotein cholesterol levels ( 33339817)
  • Mammographic density (dense area) ( 25342443)
  • Memory dysfunction in frontotemporal lobe dementia ( 29724592)
  • Metabolite levels ( 23823483)
  • Nicotine dependence ( 33144568)
  • Night sleep phenotypes ( 27126917)
  • Obesity-related traits ( 23251661)
  • Pursuit maintenance gain ( 29064472)
  • Refractive error ( 32231278)
  • Response to anti-depressant treatment in major depressive disorder ( 22041458)
  • Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125)
  • Schizophrenia ( 28991256 30285260)
  • Serum folate levels ( 29953918)
  • Total cholesterol levels ( 33339817)
  • Visceral fat ( 30942860)
Interacting Genes 25 interacting genes: ACVR2A ADGRB1 ADRB1 ARRDC3 ATN1 CRHR1 CTNNB1 CTNND2 DLGAP1 DLGAP2 DLGAP3 DLL1 DSCAML1 GRID2 MORN4 PDZD11 PLEKHF2 PLXNB3 PRRG4 PTEN RAPGEF2 RPS6KA1 SMAD3 SNRPB TGFA 198 interacting genes: ACP1 AJAP1 AKT1 AMER1 APC APC2 APP AR ARFGEF1 ARHGAP32 ARHGEF4 ASGR2 ASH2L AXIN1 AXIN2 BCL3 BCL6 BCL9 BCL9L BOC BRCA1 BTRC CA9 CARM1 CASP3 CASP8 CBL CBY1 CCND1 CCR1 CDC25A CDC27 CDC73 CDH1 CDH11 CDH15 CDH16 CDH2 CDH24 CDH3 CDH5 CDH7 CDH8 CDH9 CDK1 CDK2 CDK5 CDK5R1 CDK6 CDON CEBPA CHD8 CHUK CREBBP CSNK1A1 CSNK1D CSNK2A1 CSNK2B CTNNA1 CTNNA3 CTNNBIP1 CTNND2 DLG5 DSC3 DVL1 DVL3 EGFR ELAVL1 EP300 ERBB2 ERBIN ESR1 EZR FBXW2 FER FHIT FHL2 FLT1 FOXO1 FOXO4 FSCN1 FUS FYN GLIS2 GLUD1 GNA13 GNAI2 GRIK2 GRIN1 GRIN2D GSK3B H1-2 HIF1A HNF1A HUWE1 IGF2BP1 IKBKB IQGAP1 JADE1 KAT2A KAT2B KDR KMT2A KMT2D LAMB2 LATS2 LEF1 LEO1 MAGI1 MAGI2 MAP3K2 MAPK8 MAPK9 MEN1 MET MITF MUC1 NCOA2 NDRG1 NEK2 NEURL2 NF2 NFKB1 NOTCH1 NR5A1 PECAM1 PICK1 PIK3R1 PIN1 PITX2 PKD1 PKM PKP2 PLK1 PPM1A PRKCG PSEN1 PSEN2 PTGS2 PTPN1 PTPN13 PTPN14 PTPN6 PTPRB PTPRF PTPRJ PTPRK PTPRM PTPRU PTPRZ1 PYGO1 RAPGEF2 RBBP5 RUVBL1 RUVBL2 RXRA SALL1 SLC9A3R1 SMAD2 SMAD3 SMAD4 SMAD7 SMARCA4 SMARCA5 SMURF1 SOX1 SOX17 SP1 SPN SRC SSTR3 STUB1 TAX1BP3 TBL1X TCF3 TCF4 TCF7L1 TCF7L2 TFAP2A TGFBR1 TGFBR2 TJP1 TLE1 TRIM33 TRIM55 TRIM63 TRIP10 TRRAP TSC1 UBE2B UBE2D1 UBE2R2 UBE2S UBE3A UHRF2 USP9X ZFYVE9 ZIC3
Entrez ID 9863 1499
HPRD ID 16212 00286
Ensembl ID ENSG00000187391 ENSG00000168036
Uniprot IDs B7Z4H4 Q86UL8 A0A024R2Q3 B4DGU4 P35222
PDB IDs 1UEP 1UEQ 1UEW 1UJV 1WFV 1G3J 1JDH 1JPW 1LUJ 1P22 1QZ7 1T08 1TH1 2G57 2GL7 2Z6H 3DIW 3FQN 3FQR 3SL9 3SLA 3TX7 4DJS 6M90 6M91 6M92 6M93 6M94 6O9B 6O9C 6WLX 6WNX 7AFW
Enriched GO Terms of Interacting Partners?
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