SPOCK2 and TES

Number of citations of the paper that reports this interaction (PubMedID 12810672)
22

Data Source:
HPRD (in vivo)

		SPOCK2	TES
Description		SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2	testin LIM domain protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix	Nucleus Cytosol Plasma Membrane Focal Adhesion Cell Junction Protein-containing Complex
	Molecular Function	Calcium Ion Binding Protein Binding Glycosaminoglycan Binding Metalloendopeptidase Inhibitor Activity Extracellular Matrix Binding	RNA Binding Protein Binding Zinc Ion Binding Cadherin Binding
	Biological Process	Synapse Assembly Positive Regulation Of Cell-substrate Adhesion Negative Regulation Of Endopeptidase Activity Peptide Cross-linking Via Chondroitin 4-sulfate Glycosaminoglycan Extracellular Matrix Organization Regulation Of Cell Differentiation Cellular Response To Leukemia Inhibitory Factor Positive Regulation Of Cell Motility	Negative Regulation Of Cell Population Proliferation
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Insulin-like growth factors ( 21216879) Response to antioxidants and zinc in age-related macular degeneration (disease progression) ( 33751636) Smoking behavior ( 22832964)	Chronotype ( 30696823) Glaucoma ( 31959993 30054594) Intraocular pressure ( 31959993 30054594 29235454) Metabolite levels ( 23823483) Schizophrenia, bipolar disorder or major depressive disorder ( 34099189) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Schizophrenia, bipolar disorder or recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		3 interacting genes: PLXNB3 SPOCK3 TES	13 interacting genes: ACTL7A ACTN1 ALKBH4 ARAP1 ENAH EVL GRIPAP1 SOCS3 SPOCK2 SPTAN1 TLN1 VASP ZYX
Entrez ID		9806	26136
HPRD ID		12146	05833
Ensembl ID		ENSG00000107742	ENSG00000135269
Uniprot IDs		A0A024QZQ5 Q92563	A4D0U5 Q9UGI8
PDB IDs			2IYB 2XQN
Enriched GO Terms of Interacting Partners?
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