SNX17 and SELP

Number of citations of the paper that reports this interaction (PubMedID 11237770)
22

Data Source:
HPRD (two hybrid)

		SNX17	SELP
Description		sorting nexin 17	selectin P
Image
GO Annotations	Cellular Component	Endosome Early Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Cytoplasmic Vesicle Protein-containing Complex Intracellular Membrane-bounded Organelle	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Platelet Dense Granule Membrane Platelet Alpha Granule Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding Protein C-terminus Binding Phosphatidylinositol Binding Low-density Lipoprotein Particle Receptor Binding	Lipopolysaccharide Binding Calcium Ion Binding Protein Binding Heparin Binding Sialic Acid Binding Fucose Binding Glycosphingolipid Binding Calcium-dependent Protein Binding Oligosaccharide Binding
	Biological Process	Kidney Development Cardiac Septum Development Cholesterol Catabolic Process Intracellular Protein Transport Receptor-mediated Endocytosis Signal Transduction Endosomal Transport Regulation Of Endocytosis Endocytic Recycling Aorta Development Coronary Vasculature Development	Positive Regulation Of Leukocyte Migration Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Positive Regulation Of Platelet Activation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Response To Lipopolysaccharide Regulation Of Integrin Activation Response To Cytokine Calcium-mediated Signaling Using Intracellular Calcium Source Defense Response To Gram-negative Bacterium Leukocyte Tethering Or Rolling Positive Regulation Of Leukocyte Tethering Or Rolling
Pathways			Platelet degranulation Cell surface interactions at the vascular wall
Drugs			Heparin N-acetyl-alpha-neuraminic acid Dalteparin Nadroparin Crizanlizumab
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Crohn's disease ( 28067908) High light scatter reticulocyte count ( 27863252) Inflammatory bowel disease ( 28067908) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Microalbuminuria ( 31511532) Non-oily fish consumption ( 32066663) Refractive error ( 32231278) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Serum alkaline phosphatase levels ( 33339817) Triglyceride levels ( 32203549 32902719 34074324 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 30910378 31511532 32600054) Urinary sodium to potassium ratio ( 30910378)	Activated partial thromboplastin time ( 22703881) Blood protein levels ( 30072576 29875488 28240269) Hippocampal atrophy ( 22745009) Inflammatory bowel disease ( 26192919) L-selectin levels ( 25576479) Late-onset Alzheimer's disease ( 27770636) Monocyte count ( 32888494) Optic disc size ( 31809533) Soluble levels of adhesion molecules ( 20167578) Total ventricular volume ( 21116278)
Interacting Genes		19 interacting genes: ACE2 ANXA2 APP HOXC8 HRAS KCNG3 LDLR LRP1 LRP2 LRP8 PEX10 RABAC1 RHOB RIN1 RLIM RNF128 SELP SKIL VLDLR	11 interacting genes: AP1M1 CD24 EZR FCER1G FUT4 GP1BA SELPLG SERPING1 SNX17 SNX27 VCAN
Entrez ID		9784	6403
HPRD ID		05812	01433
Ensembl ID		ENSG00000115234	ENSG00000174175
Uniprot IDs		B4DDM3 B4DQ37 B4DTB8 Q15036	A0A024R8Y9 P16109 Q5R341 Q6NUL9
PDB IDs		3FOG 3LUI 4GXB 4TKN	1FSB 1G1Q 1G1R 1G1S 1HES 1KJD
Enriched GO Terms of Interacting Partners?
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