CCP110 and USP33

Number of citations of the paper that reports this interaction (PubMedID 23486064)
65

Data Source:
BioGRID (enzymatic study)

		CCP110	USP33
Description		centriolar coiled-coil protein 110	ubiquitin specific peptidase 33
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Centriole Cytosol Cilium Protein-containing Complex	Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol Focal Adhesion VCB Complex Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding Zinc Ion Binding Small GTPase Binding Ubiquitin Binding
	Biological Process	Centriole Replication Ciliary Basal Body Organization Regulation Of Cytokinesis Positive Regulation Of Cilium Assembly Centrosome Duplication Negative Regulation Of Cilium Assembly Negative Regulation Of Centriole Elongation	Ubiquitin-dependent Protein Catabolic Process Endocytosis Axon Guidance Regulation Of G Protein-coupled Receptor Signaling Pathway Cellular Response To Starvation Regulation Of Autophagy Cell Migration Protein Deubiquitination Negative Regulation Of Protein Binding Positive Regulation Of Protein Binding Protein Stabilization Centrosome Duplication Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Ub-specific processing proteases AURKA Activation by TPX2 RHOV GTPase cycle	Ub-specific processing proteases Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS			Adult body size ( 32376654) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		14 interacting genes: AKAP9 CALM1 CALM3 CDK1 CDK2 CEP97 CETN1 CETN2 DCAF1 ELOB PCNT PNMA1 TFIP11 USP33	16 interacting genes: CCP110 CHRM5 DDX56 DIO2 EIF6 ELOB ELOC PRKN SELENBP1 TRIM54 TRIM63 UBC USP15 USP21 USP28 VHL
Entrez ID		9738	23032
HPRD ID		10848	10297
Ensembl ID		ENSG00000103540	ENSG00000077254
Uniprot IDs		O43303	Q8TEY7
PDB IDs			2UZG
Enriched GO Terms of Interacting Partners?
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