TRAM2 and GTF2F2

Number of citations of the paper that reports this interaction (PubMedID 14612417)
3

Data Source:
HPRD (in vivo)

		TRAM2	GTF2F2
Description		translocation associated membrane protein 2	general transcription factor IIF subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Nucleoplasm Transcription Factor TFIIF Complex Microtubule Cytoskeleton Transcription Preinitiation Complex
	Molecular Function	Protein Binding	DNA Binding DNA Helicase Activity Protein Binding ATP Binding RNA Polymerase II General Transcription Initiation Factor Activity ATP Hydrolysis Activity
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Collagen Biosynthetic Process Protein Insertion Into ER Membrane	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter DNA Duplex Unwinding
Pathways			Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Viral Messenger RNA Synthesis RNA Polymerase II Pre-transcription Events TP53 Regulates Transcription of DNA Repair Genes FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE Signaling by FGFR2 IIIa TM Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Atopic march ( 26542096) Intraocular pressure ( 29617998) LDL cholesterol levels ( 28334899) Lipid traits (pleiotropy) (HIPO component 2) ( 30289880) Low density lipoprotein cholesterol levels ( 29083408) Total cholesterol levels ( 28334899)	Normal facial asymmetry (angle of surface orientation score) ( 30631343) Type 2 diabetes ( 25760438)
Interacting Genes		5 interacting genes: GTF2B GTF2F2 POLR2A PTK7 TBP	34 interacting genes: AHR AR ARNT ATF2 ATF4 CEBPG CREB1 DYNLT2B FHL2 FOS GTF2B GTF2E1 GTF2E2 GTF2F1 HMGA1 HTATSF1 JUN KLF5 MAPRE3 MSX2 MYC POLR2A POLR2E RBPMS RPL27A TAF5 TBP TCEA1 TRAM2 TSC22D1 TSPAN3 URI1 YEATS4 ZMYND19
Entrez ID		9697	2963
HPRD ID		16338	01804
Ensembl ID		ENSG00000065308	ENSG00000188342
Uniprot IDs		A0A024RD84 Q15035	A0A024RDU9 P13984
PDB IDs			1BBY 1F3U 2BBY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L
Enriched GO Terms of Interacting Partners?
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