DZIP3 and ARHGAP32

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		DZIP3	ARHGAP32
Description		DAZ interacting zinc finger protein 3	Rho GTPase activating protein 32
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Golgi Membrane Fibrillar Center Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Cell Cortex Endosome Membrane Postsynaptic Density Actin Cytoskeleton Dendritic Spine
	Molecular Function	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Phosphatase Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	GTPase Activator Activity Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Protein Polyubiquitination	Small GTPase Mediated Signal Transduction Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252)	Intracranial aneurysm ( 30823506) Iris color (L* coordinate) ( 29109912) Macular thickness ( 30535121) Metabolite levels (5-HIAA) ( 23319000) Refractive error ( 32231278)
Interacting Genes		53 interacting genes: AKTIP AP1M1 ARHGAP32 ATXN1 BAG4 BIRC2 BIRC3 CARM1 CEP63 DAZ1 FBXO17 GRIP1 GTF2H2C_2 HNRNPF HNRNPH1 HNRNPUL1 HOTAIR HOXC8 MIR20A MIR29C NCOR1 PCGF3 PITX1 RAD18 RBM4B RNF38 RUNX1 TNFRSF18 TNS2 TOLLIP TRIM21 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765	33 interacting genes: ABI2 ATXN1 BCAR1 CAMK2N2 CDC42 CDH1 CDH2 CRK CRKL CTNNB1 DLG4 DZIP3 FYN GAB1 GAB2 GRAP GRB2 GRIN2A GRIN2B LHX2 MDFI MEGF10 NCK1 NCK2 NPHP1 NTRK1 PIK3R1 PLCG1 RAC1 RHOA SHC3 SRC TLE5
Entrez ID		9666	9743
HPRD ID		10562	12257
Ensembl ID		ENSG00000198919	ENSG00000134909
Uniprot IDs		Q86Y13	A7KAX9 Q86T64
PDB IDs			3IUG
Enriched GO Terms of Interacting Partners?
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